SCHEMBL897718

SCHEMBL897718

C=C(C)C(=O)OC(CCCC)COP(=O)(O)OP(=O)(O)OCC(CCCC)OC(=O)C(=C)C

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 4/20 0.44
LPAR1 Q92633 3/20 0.44
PLA2G2A P14555 2/20 0.39
ENPP2 Q13822 5/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TSHR P16473 2/20 0.36
FABP3 P05413 1/20 0.36
PLA2G2C Q5R387 1/20 0.35
SMPD1 P17405 1/20 0.34
FDPS P14324 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15710232 0.97 LPAR3 (0.43) LPAR3LPAR1PLA2G2AENPP2SMN1; SMN2
SCHEMBL2679164 0.95 LPAR3 (0.48) LPAR3LPAR1PLA2G2AENPP2SMN1; SMN2
SCHEMBL12274757 0.94 LPAR3 (0.40) LPAR3LPAR1PLA2G2AENPP2SMN1; SMN2
SCHEMBL898942 0.92 LPAR3 (0.40) LPAR3LPAR1PLA2G2AENPP2SMN1; SMN2
SCHEMBL12273806 0.89 PLA2G2A (0.47) LPAR3LPAR1PLA2G2AENPP2SMN1; SMN2
SCHEMBL15752950 0.89 ENPP2 (0.47) LPAR3LPAR1ENPP2SMN1; SMN2
SCHEMBL12275291 0.86 TSHR (0.44) LPAR3LPAR1PLA2G2AENPP2SMN1; SMN2
SCHEMBL898473 0.85 LPAR3 (0.39) LPAR3LPAR1PLA2G2AENPP2SMN1; SMN2
SCHEMBL26109390 0.84 LPAR3 (0.49) LPAR3LPAR1ENPP2SMN1; SMN2
SCHEMBL7094395 0.83 LPAR3 (0.51) LPAR3LPAR1ENPP2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210052469-A1 POLYMERIZABLE DENTAL COMPOSITION BASED ON CONDENSED SILANES VOCO GMBH (DE) 2021-02-25 US claimed
EP-3782599-A1 DENTAL POLYMERIZABLE COMPOSITION BASED ON CONDENSED SILANES VOCO GmbH (DE) 2021-02-24 EP claimed
EP-3782599-A1 DENTAL POLYMERIZABLE COMPOSITION BASED ON CONDENSED SILANES VOCO GmbH (DE) 2021-02-24 EP disclosed
EP-2716276-B1 Kit and method for indirect chair-side production of composite inlays VOCO GMBH (DE) 2019-04-24 EP disclosed
EP-2578200-B1 Compounds for infiltrating and/or sealing of dental hard substance and method VOCO GMBH (DE) 2018-03-28 EP disclosed
EP-2436363-B1 Compound comprising a monomer with a polyalicyclic structure element for filling and/or sealing a root canal VOCO GMBH (DE) 2017-01-18 EP disclosed
US-9079828-B2 Polymerizable compounds comprising a polyalicylic structure element VOCO GMBH (DE) 2015-07-14 US disclosed
US-8979535-B2 Compositions for infiltration and/or sealing of hard tooth tissue and corresponding methods VOCO GMBH (DE) 2015-03-17 US disclosed
US-8915736-B2 Composition comprising a monomer with a polyalicyclic structure element for filling and/or sealing a root canal VOCO GMBH (DE) 2014-12-23 US disclosed
US-8697772-B2 Polymerizable phosphoric acid derivatives comprising a polyalicylic structure element VOCO GMBH (DE) 2014-04-15 US disclosed
EP-2578200-A1 Compounds for infiltrating and/or sealing of dental hard substance and method VOCO GmbH (DE) 2013-04-10 EP disclosed
EP-2450025-A1 Polymerisable phosphoric acid derivatives comprising a polyalicyclic structure element VOCO GmbH (DE) 2012-05-09 EP disclosed
US-20120082954-A1 Composition Comprising a Monomer with a Polyalicyclic Structure Element for Filling and/or Sealing a Root Canal VOCO GMBH (DE) 2012-04-05 US disclosed
US-20120082959-A1 Polymerizable Compounds Comprising a Polyalicylic Structure Element VOCO GMBH (DE) 2012-04-05 US disclosed
EP-2436668-A1 Polymerisable compounds comprising a polyalicyclic structure element VOCO GmbH (DE) 2012-04-04 EP disclosed
US-6790877-B2 Bonding compositions for dental use KURARAY CO., LTD. (JP) 2004-09-14 US disclosed
EP-0980682-B1 Bonding compositions for dental use KURARAY CO (JP) 2003-11-05 EP disclosed
US-20020035169-A1 Bonding compositions for dental use KURARAY CO., LTD (JP) 2002-03-21 US disclosed
US-6355704-B1 BACTERICIDE PRIMERS; BONDING TO TEETH KURARAY CO., LTD. (JP) 2002-03-12 US disclosed
EP-0980682-A1 Bonding compositions for dental use KURARAY CO., LTD. (JP) 2000-02-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020035169-A1 Bonding compositions for dental use PTK2, DEK, POLK LPAR3 4225/4885LPAR1 4116/4885PLA2G2A 1505/4885
US-20120082959-A1 Polymerizable Compounds Comprising a Polyalicylic Structure Element PCBP1, PUF60, PARG LPAR3 3723/4885LPAR1 3948/4885PLA2G2A 2687/4885
US-20210052469-A1 POLYMERIZABLE DENTAL COMPOSITION BASED ON CONDENSED SILANES NCAPH, RCC1, NCAPD2 LPAR3 1042/4885LPAR1 1832/4885PLA2G2A 900/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.