Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | FABP3 | P05413 | 1/20 | 0.32 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.31 |
| ▸ | PGD | P52209 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15710232 | 0.95 | LPAR3 (0.43) | LPAR3LPAR1PLA2G2ATSHRENPP2 | |
| SCHEMBL897718 | 0.92 | LPAR3 (0.44) | LPAR3LPAR1PLA2G2ATSHRENPP2 | |
| SCHEMBL2679164 | 0.89 | LPAR3 (0.48) | LPAR3LPAR1PLA2G2ATSHRENPP2 | |
| SCHEMBL898473 | 0.88 | LPAR3 (0.39) | LPAR3LPAR1PLA2G2ATSHRBTN3A1 | |
| SCHEMBL26105729 | 0.88 | ENPP2 (0.43) | LPAR3LPAR1TSHRENPP2SMN1; SMN2 | |
| SCHEMBL12274757 | 0.85 | LPAR3 (0.40) | LPAR3LPAR1PLA2G2ATSHRENPP2 | |
| SCHEMBL12273806 | 0.83 | PLA2G2A (0.47) | LPAR3LPAR1PLA2G2ATSHRENPP2 | |
| SCHEMBL2639660 | 0.81 | TSHR (0.38) | LPAR3LPAR1PLA2G2ATSHRBTN3A1 | |
| SCHEMBL15752950 | 0.79 | ENPP2 (0.47) | LPAR3LPAR1ENPP2SMN1; SMN2PGD | |
| SCHEMBL11863394 | 0.79 | ALDH1A1 (0.46) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210052469-A1 | POLYMERIZABLE DENTAL COMPOSITION BASED ON CONDENSED SILANES | VOCO GMBH (DE) | 2021-02-25 | — | — | US | claimed |
| EP-3782599-A1 | DENTAL POLYMERIZABLE COMPOSITION BASED ON CONDENSED SILANES | VOCO GmbH (DE) | 2021-02-24 | — | — | EP | claimed |
| EP-2716276-B1 | Kit and method for indirect chair-side production of composite inlays | VOCO GMBH (DE) | 2019-04-24 | — | — | EP | disclosed |
| EP-2578200-B1 | Compounds for infiltrating and/or sealing of dental hard substance and method | VOCO GMBH (DE) | 2018-03-28 | — | — | EP | disclosed |
| EP-2436363-B1 | Compound comprising a monomer with a polyalicyclic structure element for filling and/or sealing a root canal | VOCO GMBH (DE) | 2017-01-18 | — | — | EP | disclosed |
| US-9079828-B2 | Polymerizable compounds comprising a polyalicylic structure element | VOCO GMBH (DE) | 2015-07-14 | — | — | US | disclosed |
| US-8979535-B2 | Compositions for infiltration and/or sealing of hard tooth tissue and corresponding methods | VOCO GMBH (DE) | 2015-03-17 | — | — | US | disclosed |
| US-8915736-B2 | Composition comprising a monomer with a polyalicyclic structure element for filling and/or sealing a root canal | VOCO GMBH (DE) | 2014-12-23 | — | — | US | disclosed |
| US-8697772-B2 | Polymerizable phosphoric acid derivatives comprising a polyalicylic structure element | VOCO GMBH (DE) | 2014-04-15 | — | — | US | disclosed |
| EP-2578200-A1 | Compounds for infiltrating and/or sealing of dental hard substance and method | VOCO GmbH (DE) | 2013-04-10 | — | — | EP | disclosed |
| US-20130084546-A1 | COMPOSITIONS FOR INFILTRATION AND/OR SEALING OF HARD TOOTH TISSUE AND CORRESPONDING METHODS | VOCO GMBH (DE) | 2013-04-04 | — | — | US | disclosed |
| EP-2436668-B1 | Polymerisable compounds comprising a polyalicyclic structure element | VOCO GMBH (DE) | 2012-09-12 | — | — | EP | disclosed |
| US-20120115108-A1 | POLYMERIZABLE PHOSPHORIC ACID DERIVATIVES COMPRISING A POLYALICYLIC STRUCTURE ELEMENT | VOCO GMBH (DE) | 2012-05-10 | — | — | US | disclosed |
| EP-2450025-A1 | Polymerisable phosphoric acid derivatives comprising a polyalicyclic structure element | VOCO GmbH (DE) | 2012-05-09 | — | — | EP | disclosed |
| US-20120082954-A1 | Composition Comprising a Monomer with a Polyalicyclic Structure Element for Filling and/or Sealing a Root Canal | VOCO GMBH (DE) | 2012-04-05 | — | — | US | disclosed |
| US-20120082959-A1 | Polymerizable Compounds Comprising a Polyalicylic Structure Element | VOCO GMBH (DE) | 2012-04-05 | — | — | US | disclosed |
| EP-2436668-A1 | Polymerisable compounds comprising a polyalicyclic structure element | VOCO GmbH (DE) | 2012-04-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130084546-A1 | COMPOSITIONS FOR INFILTRATION AND/OR SEALING OF HARD TOOTH TISSUE AND CORRESPONDING METHODS | ITGB3, RAB5IF, CIB1 | LPAR3 4443/4885LPAR1 4641/4885PLA2G2A 1200/4885 |
| US-20120082959-A1 | Polymerizable Compounds Comprising a Polyalicylic Structure Element | PCBP1, PUF60, PARG | LPAR3 3723/4885LPAR1 3948/4885PLA2G2A 2687/4885 |
| US-20210052469-A1 | POLYMERIZABLE DENTAL COMPOSITION BASED ON CONDENSED SILANES | NCAPH, RCC1, NCAPD2 | LPAR3 1042/4885LPAR1 1832/4885PLA2G2A 900/4885 |
| US-20120115108-A1 | POLYMERIZABLE PHOSPHORIC ACID DERIVATIVES COMPRISING A POLYALICYLIC STRUCTURE ELEMENT | CAD, PCBP1, PPIP5K2 | LPAR3 3273/4885LPAR1 2921/4885PLA2G2A 2061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.