Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977302 | 1.00 | NFE2L2 (0.47) | NFE2L2MAOBMAOADRD2ADRA1D | |
| SCHEMBL30987469 | 0.74 | MAOB (0.54) | NFE2L2MAOBMAOAAPP | |
| SCHEMBL8977379 | 0.73 | DRD2 (0.43) | DRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL5213208 | 0.71 | MAOB (0.51) | NFE2L2MAOBMAOAAPP | |
| SCHEMBL9539801 | 0.71 | MAOA (0.56) | MAOBMAOA | |
| SCHEMBL1610007 | 0.71 | MAOA (0.56) | MAOBMAOA | |
| SCHEMBL8036238 | 0.71 | DRD2 (0.31) | DRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL8977320 | 0.70 | NPC1 (0.41) | MAOBMAOADRD2ADRA1DADRA1A | |
| SCHEMBL3889786 | 0.70 | OPRL1 (0.50) | MAOBMAOA | |
| SCHEMBL3889782 | 0.70 | OPRL1 (0.50) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523439-A | Process for preparing silacyclohexane compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0696592-A1 | Process for preparing silacyclohexane compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |