Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9156802 | 0.92 | MAPT (0.44) | TRPA1PGRNR3C1ARKMT2A | |
| SCHEMBL8977956 | 0.80 | ALDH1A1 (0.43) | TRPA1KMT2ATMEM97SIGMAR1TSHR | |
| SCHEMBL5093206 | 0.79 | LOXL2 (0.50) | PGRNR3C1ARKMT2ALOXL2 | |
| SCHEMBL3461796 | 0.79 | MAPT (0.49) | ALDH1A1LMNAMAPTSMN1; SMN2IDO1 | |
| SCHEMBL23146060 | 0.78 | SIGMAR1 (0.42) | KMT2ATMEM97SIGMAR1TSHRCYP1A2 | |
| SCHEMBL1747643 | 0.78 | TMEM97 (0.42) | KMT2ATMEM97SIGMAR1LOXL2TSHR | |
| SCHEMBL1081575 | 0.78 | TMEM97 (0.45) | KMT2ATMEM97SIGMAR1ALDH1A1MAPT | |
| SCHEMBL2458179 | 0.78 | TMEM97 (0.42) | KMT2ATMEM97SIGMAR1TSHRCYP2C9 | |
| SCHEMBL23146337 | 0.78 | TMEM97 (0.45) | TRPA1KMT2ATMEM97SIGMAR1TSHR | |
| SCHEMBL1081573 | 0.78 | TMEM97 (0.45) | KMT2ATMEM97SIGMAR1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2380890-A1 | New 7,8-dihydro-1,6-naphthyridin-5(6h)-one-derivatives as PDE4 inhibitors | Almirall, S.A. (ES) | 2011-10-26 | — | — | EP | disclosed |
| US-20110253549-A1 | WASHING APPARATUS AND METHOD OF DEODORIZING WASHING WATER | KANNO MINORU | 2011-10-20 | — | — | US | disclosed |