Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8978175 | 0.86 | MTNR1A (0.45) | ALDH1A1LMNAKMT2AGAANPC1 | |
| SCHEMBL9724817 | 0.74 | ELANE (0.61) | MAPTALDH1A1LMNAHTTKMT2A | |
| SCHEMBL9724815 | 0.74 | ELANE (0.61) | MAPTALDH1A1LMNAHTTKMT2A | |
| SCHEMBL10056846 | 0.73 | TSHR (0.39) | MAPTALDH1A1LMNAHSD17B10KDM4E | |
| SCHEMBL10055597 | 0.73 | TSHR (0.39) | MAPTALDH1A1LMNAHSD17B10KDM4E | |
| SCHEMBL5783639 | 0.72 | KMT2A (0.43) | MAPTALDH1A1LMNAHTTKMT2A | |
| SCHEMBL689763 | 0.72 | KMT2A (0.54) | MAPTALDH1A1LMNAHTTKMT2A | |
| SCHEMBL8972067 | 0.72 | MTNR1A (0.62) | MAPTALDH1A1ACACBACACA | |
| SCHEMBL27698503 | 0.72 | ALDH1A1 (0.47) | ALDH1A1LMNAHSD17B10RAB9AELANE | |
| SCHEMBL8978262 | 0.72 | SLC15A1 (0.53) | ALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0378930-B1 | Cyclic urea derivative | NIPPON PAINT CO LTD (JP) | 1996-05-08 | — | — | EP | disclosed |
| US-5385985-A | Cyclic urea derivative | NIPPON PAINT CO., LTD. (JP) | 1995-01-31 | — | — | US | disclosed |
| EP-0378930-A1 | Cyclic urea derivative | NIPPON PAINT CO., LTD. (JP) | 1990-07-25 | — | — | EP | disclosed |