Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8978180 | 0.86 | MAPT (0.41) | SMN1; SMN2ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL8972067 | 0.86 | MTNR1A (0.62) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL8971806 | 0.84 | ACACB (0.46) | MTNR1AMTNR1BSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL8971765 | 0.83 | ALDH1A1 (0.54) | MTNR1AMTNR1BSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL8972162 | 0.80 | CTSK (0.45) | — | |
| SCHEMBL27470015 | 0.79 | ALDH1A1 (0.43) | MTNR1AMTNR1BSMN1; SMN2ALDH1A1CYP19A1 | |
| SCHEMBL8978262 | 0.79 | SLC15A1 (0.53) | SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL8971830 | 0.79 | ELANE (0.55) | NPC1RAB9AELANE | |
| SCHEMBL27502115 | 0.78 | SLC1A3 (0.46) | MTNR1AMTNR1BALDH1A1CYP19A1PRSS1 | |
| SCHEMBL666155 | 0.78 | POLB (0.47) | MTNR1AMTNR1BALDH1A1CYP19A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0378930-B1 | Cyclic urea derivative | NIPPON PAINT CO LTD (JP) | 1996-05-08 | — | — | EP | disclosed |
| EP-0376751-B1 | Polymerizable cyclic urea derivatives and polymers having a pendant urea | NIPPON PAINT CO LTD (JP) | 1995-02-08 | — | — | EP | disclosed |
| US-5385985-A | Cyclic urea derivative | NIPPON PAINT CO., LTD. (JP) | 1995-01-31 | — | — | US | disclosed |
| US-5179184-A | Polymerizable cyclic urea derivatives and polymers having a pendant urea | NIPPON PAINT CO., LTD. (JP) | 1993-01-12 | — | — | US | disclosed |
| US-5098949-A | Protective coatings for metals | NIPPON PAINT CO., LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| US-5030726-A | Polymerizable cyclic urea derivatives | NIPPON PAINT CO., LTD. (JP) | 1991-07-09 | — | — | US | disclosed |
| EP-0378930-A1 | Cyclic urea derivative | NIPPON PAINT CO., LTD. (JP) | 1990-07-25 | — | — | EP | disclosed |
| EP-0377337-A1 | Aqueous coating composition | NIPPON PAINT CO., LTD. (JP) | 1990-07-11 | — | — | EP | disclosed |
| EP-0376751-A1 | Polymerizable cyclic urea derivatives and polymers having a pendant urea | NIPPON PAINT CO., LTD. (JP) | 1990-07-04 | — | — | EP | disclosed |