Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8978544 | 0.80 | ALDH1A1 (1.00) | ALDH1A1PKMKDM4EGAAPOLB | |
| SCHEMBL8978582 | 0.78 | ALDH1A1 (0.71) | ALDH1A1PKMKDM4EGAAPOLB | |
| SCHEMBL9222791 | 0.78 | ALDH1A1 (0.71) | ALDH1A1PKMKDM4EGAAPOLB | |
| SCHEMBL3417595 | 0.73 | ALDH1A1 (0.64) | ALDH1A1PKMKDM4EGAAPOLB | |
| SCHEMBL919250 | 0.73 | HSD17B10 (0.73) | ALDH1A1PKMKDM4EGAAPOLB | |
| SCHEMBL378177 | 0.71 | KDM4E (0.66) | ALDH1A1PKMKDM4EGAAPOLB | |
| SCHEMBL13984004 | 0.68 | ALDH1A1 (0.57) | ALDH1A1PKMKDM4EGAAHSD17B10 | |
| SCHEMBL2919461 | 0.66 | MAPT (0.52) | ALDH1A1KDM4EGAAPOLBNPSR1 | |
| SCHEMBL28757255 | 0.66 | ALOX15 (0.40) | ALDH1A1KDM4EGAAPOLBNPSR1 | |
| SCHEMBL12768241 | 0.66 | KDM4E (0.76) | ALDH1A1PKMKDM4EGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489598-A | INHIBITS ADHESION OF MAC-1 TO ENDOTHELIAL CELLS, USEFUL FOR TREATING GASTRITIS INDUCED BY NONSTEROIDANTIINFLAMMATORY DRUGS IMFLAMMATORY BOWEL DISEASE OF ULCERATIVE COLITIS | WARNER-LAMBERT COMPANY (US) | 1996-02-06 | — | — | US | disclosed |