Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM2 | O94759 | 2/20 | 0.58 |
| ▸ | SLC28A2 | O43868 | 9/20 | 0.56 |
| ▸ | HSPA8 | P11142 | 2/20 | 0.56 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.54 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.49 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.49 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.47 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19699266 | 0.87 | DNPH1 (0.46) | TRPM2SLC28A2HSPA8SIRT2SIRT1 | |
| SCHEMBL8979282 | 0.87 | TRPM2 (0.61) | TRPM2SIRT2SIRT1POLBADORA3 | |
| SCHEMBL6758895 | 0.86 | SLC28A2 (0.71) | SLC28A2HSPA8ADORA3ADORA2A | |
| SCHEMBL6758906 | 0.86 | SLC28A2 (0.71) | SLC28A2HSPA8ADORA3ADORA2A | |
| SCHEMBL1881041 | 0.84 | POLB (0.52) | TRPM2SIRT2SIRT1POLBDNPH1 | |
| SCHEMBL2571716 | 0.82 | SLC28A2 (0.74) | SLC28A2HSPA8ADORA3ADORA2A | |
| SCHEMBL2571711 | 0.82 | SLC28A2 (0.74) | SLC28A2HSPA8ADORA3ADORA2A | |
| SCHEMBL31685404 | 0.82 | POLB (0.58) | TRPM2SIRT2SIRT1POLBADORA3 | |
| SCHEMBL16208897 | 0.81 | POLB (0.57) | TRPM2SIRT2SIRT1POLBDNPH1 | |
| SCHEMBL16208893 | 0.81 | POLB (0.57) | TRPM2SIRT2SIRT1POLBDNPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10342819-B2 | Oligonucleotide having non-natural nucleotide at 5′-terminal thereof | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2019-07-09 | — | — | US | disclosed |
| US-20170354673-A1 | OLIGONUCLEOTIDE HAVING NON-NATURAL NUCLEOTIDE AT 5'-TERMINAL THEREOF | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2017-12-14 | — | — | US | disclosed |
| US-20170354673-A1 | OLIGONUCLEOTIDE HAVING NON-NATURAL NUCLEOTIDE AT 5'-TERMINAL THEREOF | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2017-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10342819-B2 | Oligonucleotide having non-natural nucleotide at 5′-terminal thereof | RNGTT, UPF1, NSUN3 | TRPM2 4847/4885SLC28A2 305/4885HSPA8 1604/4885 |
| US-20170354673-A1 | OLIGONUCLEOTIDE HAVING NON-NATURAL NUCLEOTIDE AT 5'-TERMINAL THEREOF | RNGTT, UPF1, NSUN3 | TRPM2 4843/4885SLC28A2 314/4885HSPA8 1590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.