Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | DUT | P33316 | 2/20 | 0.31 |
| ▸ | TK1 | P04183 | 2/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10802176 | 0.89 | CA1 (0.39) | MEN1KMT2AKIF11PLA2G2APLA2G10 | |
| SCHEMBL10805897 | 0.89 | ALOX15 (0.34) | MEN1KMT2AKIF11PLA2G2APLA2G10 | |
| SCHEMBL8174806 | 0.87 | KIF11 (0.38) | MEN1KMT2AKIF11PLA2G2APLA2G10 | |
| SCHEMBL8175157 | 0.87 | KIF11 (0.38) | MEN1KMT2AKIF11PLA2G2APLA2G10 | |
| SCHEMBL8979363 | 0.86 | PLA2G2A (0.49) | MEN1KMT2AKIF11PLA2G2APLA2G10 | |
| SCHEMBL2619910 | 0.82 | MEN1 (0.43) | MEN1KMT2AKIF11ALDH1A1TSHR | |
| SCHEMBL8004769 | 0.82 | AOC3 (0.37) | KIF11PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL27859924 | 0.81 | CA1 (0.45) | KIF11ALDH1A1TSHRHTTCYP2D6 | |
| SCHEMBL8004766 | 0.77 | PGR (0.32) | — | |
| SCHEMBL10565436 | 0.77 | TSHR (0.37) | MEN1KMT2AKIF11ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710225-A1 | FLUORESCENCE DETERMINATION OF THE ACTIVITY OF LIPOLYTIC ENZYMES | PROGEN Biotechnik GmbH (DE) | 1996-05-08 | — | — | EP | disclosed |
| WO-1995032181-A1 | FLUORESCENCE DETERMINATION OF THE ACTIVITY OF LIPOLYTIC ENZYMES | PROGEN BIOTECHNIK GMBH (DE) | 1995-11-30 | — | — | WO | disclosed |