SCHEMBL8979796

SCHEMBL8979796

CS(=O)(=O)Nc1cccc(SCc2ccccc2)n1

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CXCR2 P25025 8/20 0.53
KDM4E B2RXH2 3/20 0.47
ALDH1A1 P00352 3/20 0.47
HPGD P15428 2/20 0.47
PKM P14618 2/20 0.45
LMNA P02545 2/20 0.45
MAPT P10636 1/20 0.45
KMT2A Q03164 1/20 0.45
PTGS2 P35354 1/20 0.42
ABL1 P00519 1/20 0.40
RIN1 Q13671 1/20 0.40
HSD17B10 Q99714 2/20 0.39
KEAP1 Q14145 1/20 0.39
CA1 P00915 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8979773 0.87 HPGD (0.52) CXCR2KDM4EALDH1A1HPGDPKM
SCHEMBL8979904 0.78 KMT2A (0.44) ALDH1A1HPGDPKMLMNAMAPT
SCHEMBL19925108 0.77 KMT2A (0.47) CXCR2ALDH1A1HPGDPKMLMNA
SCHEMBL9868149 0.74 PTGS2 (0.42) CXCR2HPGDPKMLMNAMAPT
SCHEMBL489440 0.73 CXCR2 (0.67) CXCR2
SCHEMBL31404939 0.72 LMNA (0.50) KDM4EALDH1A1HPGDPKMLMNA
SCHEMBL2408695 0.72 LMNA (0.50) KDM4EALDH1A1HPGDPKMLMNA
SCHEMBL8979765 0.71 ALDH1A1 (0.44) CXCR2ALDH1A1HPGDPKMLMNA
SCHEMBL30611778 0.71 SCN9A (0.48) KDM4EALDH1A1PKMLMNAMAPT
SCHEMBL490035 0.70 CXCR2 (1.00) CXCR2ALDH1A1LMNAMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5583231-A HERBICIDE ISHIHARA SANGYO KAISHA, LTD. (JP) 1996-12-10 US disclosed
US-5457084-A Herbicides use at low dosage ISHIHARA SANGYO KAISHA LTD. (JP) 1995-10-10 US disclosed
EP-0496608-B1 Substituted pyridinesulfonamide compound or its salt, process for preparing the same, and herbicide containing the same ISHIHARA SANGYO KAISHA (JP) 1995-09-20 EP disclosed
US-5348933-A Triazine substituted compounds ISHIHARA SANGYO KAISHA, LTD. (JP) 1994-09-20 US disclosed
EP-0496608-A1 Substituted pyridinesulfonamide compound or its salt, process for preparing the same, and herbicide containing the same ISHIHARA SANGYO KAISHA, Ltd. (JP) 1992-07-29 EP disclosed