SCHEMBL8979904

SCHEMBL8979904

CCNc1cccc(SCc2ccccc2)n1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
PKM P14618 1/20 0.44
KCNH2 Q12809 1/20 0.42
CACNA1C Q13936 1/20 0.42
SCN5A Q14524 1/20 0.42
TP53 P04637 2/20 0.41
TSHR P16473 1/20 0.41
RAB9A P51151 4/20 0.40
METAP2 P50579 1/20 0.40
HSD17B10 Q99714 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
NPC1 O15118 2/20 0.38
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
HSP90AA1 P07900 1/20 0.38
ADORA3 P0DMS8 2/20 0.38
ABL1 P00519 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8979773 0.80 HPGD (0.52) KMT2ALMNAMAPTPKMTSHR
SCHEMBL8979796 0.78 CXCR2 (0.53) KMT2ALMNAMAPTPKMHSD17B10
SCHEMBL19925108 0.77 KMT2A (0.47) KMT2ALMNAMAPTPKMTSHR
SCHEMBL2408695 0.75 LMNA (0.50) KMT2ALMNAMAPTPKMTP53
SCHEMBL31404939 0.75 LMNA (0.50) KMT2ALMNAMAPTPKMTP53
SCHEMBL30611778 0.74 SCN9A (0.48) KMT2ALMNAMAPTPKMTSHR
SCHEMBL14518469 0.73 SCN5A (0.66) KMT2AMAPTKCNH2CACNA1CSCN5A
SCHEMBL3013110 0.71 HTR1A (0.51) KMT2ALMNAMAPTPKMTP53
SCHEMBL2239049 0.71 HSD17B10 (0.44) KMT2ALMNAMAPTPKMTP53
SCHEMBL29464867 0.71 RAB9A (0.56) KMT2ALMNAMAPTPKMTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1038012-C Substiuted pyridinesulfonamide compound or its salt, process for preparing same, and herbicide coutaining same ISHIHARA SANGYO KAISHA (JP) 1998-04-15 CN disclosed
US-5583231-A HERBICIDE ISHIHARA SANGYO KAISHA, LTD. (JP) 1996-12-10 US disclosed
US-5457084-A Herbicides use at low dosage ISHIHARA SANGYO KAISHA LTD. (JP) 1995-10-10 US disclosed
EP-0496608-B1 Substituted pyridinesulfonamide compound or its salt, process for preparing the same, and herbicide containing the same ISHIHARA SANGYO KAISHA (JP) 1995-09-20 EP disclosed
US-5348933-A Triazine substituted compounds ISHIHARA SANGYO KAISHA, LTD. (JP) 1994-09-20 US disclosed
CN-1077453-A Substituted pyridinesulfonamide compound or its salt prepare its method and the weedicide that contains it ISHIHARA SANGYO KAISHA (JP) 1993-10-20 CN disclosed
EP-0562731-A1 Substituted pyridinesulfonamide compounds or their salts, process for preparing the same, and herbicides containing the same ISHIHARA SANGYO KAISHA, Ltd. (JP) 1993-09-29 EP disclosed
CN-1064274-A The pyridinesulfonamide compound or its salt, their preparation method and the weedicide that contains above-claimed cpd that replace ISHIHARA SANGYO KAISHA (JP) 1992-09-09 CN disclosed
EP-0496608-A1 Substituted pyridinesulfonamide compound or its salt, process for preparing the same, and herbicide containing the same ISHIHARA SANGYO KAISHA, Ltd. (JP) 1992-07-29 EP disclosed