SCHEMBL8979773

SCHEMBL8979773

CCS(=O)(=O)Nc1cccc(SCc2ccccc2)n1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.52
KDM4E B2RXH2 3/20 0.52
ALDH1A1 P00352 3/20 0.52
CXCR2 P25025 7/20 0.44
KMT2A Q03164 3/20 0.44
LMNA P02545 2/20 0.44
MAPT P10636 2/20 0.44
PKM P14618 1/20 0.44
RAB9A P51151 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
NPC1 O15118 1/20 0.42
TSHR P16473 1/20 0.42
HTT P42858 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
PTGS2 P35354 1/20 0.41
ABL1 P00519 1/20 0.40
RIN1 Q13671 1/20 0.40
MEN1 O00255 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8979796 0.87 CXCR2 (0.53) HPGDKDM4EALDH1A1CXCR2KMT2A
SCHEMBL8979904 0.80 KMT2A (0.44) HPGDALDH1A1KMT2ALMNAMAPT
SCHEMBL19925108 0.75 KMT2A (0.47) HPGDALDH1A1CXCR2KMT2ALMNA
SCHEMBL31404939 0.71 LMNA (0.50) HPGDKDM4EALDH1A1KMT2ALMNA
SCHEMBL2408695 0.71 LMNA (0.50) HPGDKDM4EALDH1A1KMT2ALMNA
SCHEMBL9868149 0.70 PTGS2 (0.42) HPGDCXCR2KMT2ALMNAMAPT
SCHEMBL8979765 0.70 ALDH1A1 (0.44) HPGDALDH1A1CXCR2KMT2ALMNA
SCHEMBL8979914 0.70 KMT2A (0.39) HPGDALDH1A1KMT2ALMNAMAPT
SCHEMBL30611778 0.70 SCN9A (0.48) KDM4EALDH1A1KMT2ALMNAMAPT
SCHEMBL8979899 0.68 PTGS2 (0.38) HPGDALDH1A1CXCR2KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5583231-A HERBICIDE ISHIHARA SANGYO KAISHA, LTD. (JP) 1996-12-10 US disclosed
US-5457084-A Herbicides use at low dosage ISHIHARA SANGYO KAISHA LTD. (JP) 1995-10-10 US disclosed
EP-0496608-B1 Substituted pyridinesulfonamide compound or its salt, process for preparing the same, and herbicide containing the same ISHIHARA SANGYO KAISHA (JP) 1995-09-20 EP disclosed
US-5348933-A Triazine substituted compounds ISHIHARA SANGYO KAISHA, LTD. (JP) 1994-09-20 US disclosed
EP-0496608-A1 Substituted pyridinesulfonamide compound or its salt, process for preparing the same, and herbicide containing the same ISHIHARA SANGYO KAISHA, Ltd. (JP) 1992-07-29 EP disclosed