Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 3/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979747 | 0.86 | BRS3 (0.54) | BRS3AGTR1AGTR2 | |
| SCHEMBL8979837 | 0.85 | BRS3 (0.42) | BRS3AGTR1AGTR2 | |
| SCHEMBL8979771 | 0.81 | BRS3 (0.49) | BRS3AGTR1AGTR2 | |
| SCHEMBL8979781 | 0.76 | AGTR1 (0.48) | BRS3AGTR1AGTR2 | |
| SCHEMBL8979813 | 0.73 | ACHE (0.46) | AGTR1AGTR2 | |
| SCHEMBL8979903 | 0.71 | BRS3 (0.47) | BRS3AGTR1AGTR2 | |
| SCHEMBL8979750 | 0.71 | AGTR2 (0.55) | BRS3AGTR1AGTR2 | |
| SCHEMBL8979757 | 0.70 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL11527291 | 0.70 | SMN1; SMN2 (0.49) | — | |
| SCHEMBL9198419 | 0.70 | BRS3 (0.53) | BRS3AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565464-A | Compounds having angiotensine II antagonistic activity | ISTITUTO LUSO FARMACO D'ITALIA S.P.A. (IT) | 1996-10-15 | — | — | US | disclosed |