SCHEMBL8980290

SCHEMBL8980290

Cc1ccc2ocnc2c1C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIN1 Q13526 1/20 0.39
ALDH1A1 P00352 5/20 0.37
MEN1 O00255 1/20 0.37
GAA P10253 1/20 0.37
KMT2A Q03164 1/20 0.37
SMN1; SMN2 Q16637 4/20 0.34
NPC1 O15118 3/20 0.34
RAB9A P51151 3/20 0.34
CTNNB1 P35222 1/20 0.34
WNT3A P56704 1/20 0.34
MTNR1A P48039 1/20 0.34
MTNR1B P49286 1/20 0.34
KDM4E B2RXH2 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
XDH P47989 1/20 0.33
SLC22A12 Q96S37 1/20 0.33
MAPK1 P28482 1/20 0.33
SLC26A4 O43511 1/20 0.32
LMNA P02545 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8980214 0.76 ADORA2A (0.40) PIN1ALDH1A1MEN1GAAKMT2A
SCHEMBL5070680 0.74 HTR2A (0.36) MTNR1AMTNR1BKDM4EMAPK1HTR2A
SCHEMBL22362952 0.71 HTR2A (0.34) HTR2AHTR2C
SCHEMBL30736022 0.71 LMNA (0.44) MEN1KMT2ALMNAHTR2AHTR2C
SCHEMBL27755479 0.70 ALDH1A1 (0.34) ALDH1A1MEN1KMT2ASMN1; SMN2NPC1
SCHEMBL3392120 0.70 TDP1 (0.48) ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E
SCHEMBL24206516 0.69 HTR2A (0.31) HTR2AHTR2C
SCHEMBL8660847 0.69 CA12 (0.49) PIN1ALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL20837259 0.68 KCNC1 (0.34) HTR2AHTR2C
SCHEMBL21846118 0.68 HTR2A (0.33) HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0591786-B1 Photosensitive composition FUJI PHOTO FILM CO LTD (JP) 1996-05-15 EP disclosed
EP-0591786-A2 Photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1994-04-13 EP disclosed