Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 4/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8595093 | 0.79 | ACE (0.51) | KMT2AACE | |
| SCHEMBL7745199 | 0.74 | ACE (0.47) | KMT2AACE | |
| SCHEMBL2028236 | 0.74 | ACE (0.47) | KMT2AACE | |
| SCHEMBL9067249 | 0.73 | GPR139 (0.47) | KMT2AACE | |
| SCHEMBL8980460 | 0.72 | KMT2A (0.46) | KMT2AACE | |
| SCHEMBL29151574 | 0.71 | KMT2A (0.55) | SLC1A1SLC1A3SLC1A2ALPIPKM | |
| SCHEMBL10720961 | 0.71 | KMT2A (0.38) | KMT2AACE | |
| SCHEMBL6623673 | 0.70 | SLC1A3 (0.50) | SLC1A1SLC1A3SLC1A2ALPIPKM | |
| SCHEMBL7715391 | 0.69 | GRM2 (0.53) | SLC1A1SLC1A3SLC1A2ALPIPKM | |
| SCHEMBL7207824 | 0.68 | TDP1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534497-A | RADIOPHARMACEUTICALS; MEDICAL DIAGNOSIS | MALLINCKRODT MEDICAL, INC. (US) | 1996-07-09 | — | — | US | disclosed |
| US-5187264-A | Technetium chelates to be used for determining the renal function | MALLINCKRODT MEDICAL, INC. (US) | 1993-02-16 | — | — | US | disclosed |
| EP-0250013-B1 | TECHNETIUM CHELATES TO BE USED FOR DETERMINING THE RENAL FUNCTION | MALLINCKRODT, INC.(a Missouri corporation) (US) | 1990-05-09 | — | — | EP | disclosed |
| US-4849511-A | Technetium chelates to be used for determining the renal function | MALLINCKRODT, INC. (US) | 1989-07-18 | — | — | US | disclosed |
| EP-0250013-A1 | Technetium chelates to be used for determining the renal function | MALLINCKRODT, INC.(a Missouri corporation) (US) | 1987-12-23 | — | — | EP | disclosed |