Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | NAAA | Q02083 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.50 |
| ▸ | CTSG | P08311 | 2/20 | 0.50 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.50 |
| ▸ | CMA1 | P23946 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7272796 | 0.87 | GPR139 (0.60) | GAALMNAPOLBNPC1RAB9A | |
| SCHEMBL6538970 | 0.86 | NR1H4 (0.51) | GAALMNAPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL7749756 | 0.85 | TP53 (0.62) | GAALMNAPOLBNPC1RAB9A | |
| SCHEMBL407772 | 0.84 | LMNA (0.46) | GAALMNAPOLBNPC1RAB9A | |
| SCHEMBL7272801 | 0.83 | LMNA (0.62) | GAALMNAPOLBNPC1RAB9A | |
| SCHEMBL885016 | 0.82 | CA12 (0.62) | GAALMNAPOLBNPC1RAB9A | |
| SCHEMBL3993028 | 0.82 | LMNA (0.59) | GAALMNAPOLBNPC1RAB9A | |
| SCHEMBL2863808 | 0.82 | GAA (0.61) | GAALMNAPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL28844088 | 0.82 | GAA (0.61) | GAALMNAPOLBNPC1RAB9A | |
| SCHEMBL8374747 | 0.82 | GFER (0.55) | GAALMNANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109369436-A | A kind of amide replaces alpine yarrow herb ketoacid derivatives and preparation method and purposes | 中国科学院新疆理化技术研究所 | 2019-02-22 | — | — | CN | claimed |
| US-8877891-B2 | Method of producing a novel opioid peptide | LIPKOWSKI ANDREJ (PL) | 2014-11-04 | — | — | US | claimed |
| EP-2384334-B1 | A METHOD OF PRODUCING A NOVEL OPIOID PEPTIDE | ACTION FOR DEV OF RESARCH SP Z O O (PL) | 2013-02-27 | — | — | EP | claimed |
| US-20120004180-A1 | METHOD OF PRODUCING A NOVEL OPIOID PEPTIDE | LIPKOWSKI ANDREJ (PL) | 2012-01-05 | — | — | US | claimed |
| EP-2384334-A1 | A METHOD OF PRODUCING A NOVEL OPIOID PEPTIDE | Action For Development Of Resarch SP.Z.O.O. (PL) | 2011-11-09 | — | — | EP | claimed |
| WO-2010077154-A1 | A METHOD OF PRODUCING A NOVEL OPIOID PEPTIDE | ACTION FOR DEVELOPMENT OF RESARCH SP.Z.O.O. (PL) | 2010-07-08 | — | — | WO | claimed |
| EP-1939197-A1 | 8-ethinylxanthine derivatives as selective A2A receptor antagonists | SCHWARZ PHARMA AG (DE) | 2008-07-02 | — | — | EP | claimed |
| US-20040186061-A1 | Novel derivatives of 3,3-diphenylpropylamines | SCHWARZ PHARMA AG | 2004-09-23 | — | — | US | claimed |
| US-6740305-B1 | FEEDING PATIENT MEAL INCLUDING, AS BREATH TEST FOOD ADDITIVE SUBSTRATE, LINEAR ACYL AMINOACID PEPTIDOMIMETIC WITH RADIOACTIVE OR NON-RADIOACTIVELY LABELED CARBON ATOM, DETECTING LEVEL OF LABELED CARBON DIOXIDE IN BREATH SAMPLES | XANTHUS LIFE SCIENES, INC. | 2004-05-25 | — | — | US | claimed |
| EP-1254890-A1 | Derivatives of 3,3-diphenylpropylamines | SCHWARZ PHARMA AG (DE) | 2002-11-06 | — | — | EP | claimed |
| EP-0998946-A1 | Non-porphyrin compound for use as a diagnosticum and/or pharmaceutical | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2000-05-10 | — | — | EP | claimed |
| WO-2000009169-A1 | NON-PORPHYRIN COMPOUND FOR USE AS A DIAGNOSTICUM AND/OR PHARMACEUTICAL | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2000-02-24 | — | — | WO | claimed |
| WO-1999058478-A1 | NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES | SCHWARZ PHARMA AG (DE) | 1999-11-18 | — | — | WO | claimed |
| EP-0957073-A1 | Novel derivatives of 3,3-diphenylpropylamines | SCHWARZ PHARMA AG (DE) | 1999-11-17 | — | — | EP | claimed |
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | claimed |
| EP-0253882-A4 | ACYLATED CYANAMIDE COMPOSITION. | UNIV MINNESOTA (US) | 1990-06-27 | — | — | EP | claimed |
| US-4870056-A | DETERRENTS OF ALCOHOL ABUSE | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1989-09-26 | — | — | US | claimed |
| EP-0253882-A1 | ACYLATED CYANAMIDE COMPOSITION | THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1988-01-27 | — | — | EP | claimed |
| WO-1987004348-A1 | ACYLATED CYANAMIDE COMPOSITION | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1987-07-30 | — | — | WO | claimed |
| US-4251628-A | HYDROLYSIS OF OLIGOPEPTIDES FOR RADIOISOTOPE ASSAY | VENTREX LABORATORIES, INC. | 1981-02-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186061-A1 | Novel derivatives of 3,3-diphenylpropylamines | ADRB3, ADRA1D, TNNC1 | GAA 3071/4885LMNA 3143/4885POLB 2030/4885 |
| US-20120004180-A1 | METHOD OF PRODUCING A NOVEL OPIOID PEPTIDE | OPRL1, OPRK1, OGFR | GAA 3809/4885LMNA 4311/4885POLB 4579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.