Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 8/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31619650 | 0.86 | KDM4E (0.59) | KDM4EGAAMAPTPOLBPKM | |
| SCHEMBL1628395 | 0.85 | ALDH1A1 (0.67) | KDM4EGAAMAPTPOLBPKM | |
| SCHEMBL8983948 | 0.75 | ALDH1A1 (0.56) | KDM4EGAAMAPTPOLBALDH1A1 | |
| SCHEMBL5990665 | 0.75 | ALDH1A1 (0.49) | KDM4EGAAMAPTPOLBPKM | |
| SCHEMBL5269765 | 0.74 | KDM4E (0.60) | KDM4EGAAMAPTPOLBPKM | |
| SCHEMBL7941853 | 0.73 | KDM4E (0.69) | KDM4EGAAMAPTPOLBPKM | |
| SCHEMBL3772637 | 0.72 | KDM4E (1.00) | KDM4EGAAMAPTPOLBPKM | |
| 2-Methyl-5,7,8-Trimethoxyisoflavone SCHEMBL4283593 | 0.71 | ALDH1A1 (1.00) | KDM4EGAAMAPTPKMALDH1A1 | |
| SCHEMBL18710519 | 0.71 | MAOA (0.49) | MAOA | |
| SCHEMBL5267565 | 0.70 | KDM4E (0.75) | KDM4EGAAMAPTPOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710234-A1 | ISOFLAVONE DERIVATIVES | CHINOIN LTD. (HU) | 1996-05-08 | — | — | EP | disclosed |
| WO-1995003293-A1 | ISOFLAVONE DERIVATIVES | CHINOIN LTD. (HU) | 1995-02-02 | — | — | WO | disclosed |