Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | BCL9 | O00512 | 4/20 | 0.56 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | PLK1 | P53350 | 1/20 | 0.54 |
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31065460 | 0.81 | ALDH1A1 (0.68) | ALDH1A1CYP3A4BCL9CTNNB1ACHE | |
| SCHEMBL1628395 | 0.80 | ALDH1A1 (0.67) | ALDH1A1CYP3A4BCL9CTNNB1CYP1A2 | |
| SCHEMBL28011841 | 0.78 | ACHE (0.79) | ALDH1A1CYP3A4ACHEPLK1BACE1 | |
| SCHEMBL31619650 | 0.73 | KDM4E (0.59) | ALDH1A1CYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8983906 | 0.71 | KDM4E (0.56) | ALDH1A1CYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL737207 | 0.71 | ADORA3 (0.58) | ALDH1A1CYP3A4ALOX5CYP2C9CYP2C19 | |
| SCHEMBL4287360 | 0.71 | ALDH1A1 (0.55) | ALDH1A1CYP3A4ALOX5ABCB1ABCG2 | |
| SCHEMBL5951260 | 0.71 | PDE4B (0.59) | ALDH1A1CYP3A4BCL9CTNNB1MEN1 | |
| SCHEMBL16894627 | 0.71 | ADORA3 (0.64) | ALDH1A1CYP3A4BCL9CTNNB1ALOX5 | |
| Moslosooflavone SCHEMBL6070206 | 0.70 | ACHE (1.00) | ALDH1A1CYP3A4ACHEPLK1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143279-A1 | Methods and compositions for treating metabolic disorders | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143279-A1 | Methods and compositions for treating metabolic disorders | PC, PCK2, CS | ALDH1A1 860/4885CYP3A4 2876/4885BCL9 3219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.