SCHEMBL8984589

SCHEMBL8984589

O=C(O)c1cc2c(cc1C(=O)O)C1(c3cc(C(=O)O)c(C(=O)O)cc3O2)c2ccccc2-c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.41
THRB P10828 1/20 0.41
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
MAPT P10636 2/20 0.39
HTT P42858 2/20 0.39
FTO Q9C0B1 2/20 0.39
HPGD P15428 1/20 0.39
CYP2C19 P33261 1/20 0.39
RECQL P46063 1/20 0.39
BLM P54132 1/20 0.39
SMAD3 P84022 1/20 0.39
PRMT1 Q99873 1/20 0.39
ACE2 Q9BYF1 1/20 0.39
ALOX5 P09917 2/20 0.39
CYP2C9 P11712 1/20 0.38
USP2 O75604 3/20 0.37
POLB P06746 2/20 0.37
HSD17B10 Q99714 2/20 0.37
HSP90AA1 P07900 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3274334 0.83 ALOX5 (0.41) TDP1MEN1KMT2AMAPTHPGD
SCHEMBL24183986 0.83 THRB (0.46) TDP1THRBMEN1KMT2AMAPT
SCHEMBL16347732 0.83 THRB (0.46) TDP1THRBMEN1KMT2AMAPT
SCHEMBL24285407 0.82 ESR1 (0.43) TDP1THRBMEN1KMT2AMAPT
SCHEMBL8984429 0.79 ALOX5 (0.51) TDP1THRBMEN1KMT2AHTT
SCHEMBL8984588 0.79 PDK2 (0.52) TDP1THRBMEN1KMT2AMAPT
SCHEMBL38651343 0.77 ALDH1A1 (0.52) TDP1THRBMAPTHPGDCYP2C9
SCHEMBL2709809 0.77 ALDH1A1 (0.52) TDP1THRBMAPTHPGDCYP2C9
SCHEMBL26072576 0.75 KMT2A (0.44) TDP1MEN1KMT2AMAPTHTT
SCHEMBL9347525 0.75 ALOX5 (0.50) MEN1KMT2AALOX5POLBPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5578737-A SUBSTITUTED FLUORENES, MONOMERS FOR HIGH PERFORMANCE POLYMERS THE DOW CHEMICAL COMPANY (US) 1996-11-26 US claimed
US-12091507-B2 Polymers for use in electronic devices DUPONT ELECTRONICS, INC. (US) 2024-09-17 US disclosed
CN-117500880-A Resin composition, varnish, laminated plate, printed wiring board and molded article 普林科技有限公司 2024-02-02 CN disclosed
US-11530228-B2 Tetracarboxylic acid dianhydride and method for preparing the same SK INNOVATION CO., LTD. (KR) 2022-12-20 US disclosed
US-20220010071-A1 Polyimide Precursor, Polyimide Precursor Composition, Polyimide Film, Method for Preparing the Same, and Use Thereof SK IE TECHNOLOGY CO., LTD. (KR) 2022-01-13 US disclosed
US-20220009943-A1 Tetracarboxylic Acid Dianhydride and Method for Preparing the Same SK INNOVATION CO., LTD. (KR) 2022-01-13 US disclosed
CN-112424261-A Polymers for use in electronic devices 杜邦电子公司 2021-02-26 CN disclosed
US-20210017335-A1 Polymers For Use In Electronic Devices U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2021-01-21 US disclosed
US-20210017335-A1 Polymers For Use In Electronic Devices U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2021-01-21 US disclosed
WO-2019195148-A1 POLYMERS FOR USE IN ELECTRONIC DEVICES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2019-10-10 WO disclosed
US-5578737-A SUBSTITUTED FLUORENES, MONOMERS FOR HIGH PERFORMANCE POLYMERS THE DOW CHEMICAL COMPANY (US) 1996-11-26 US disclosed
US-5387725-A Chlorinating compounds having acidic protons with a perchloro-alkane and aqueous base in the presence of a tetraalkyl-ammonium hydroxide phase transfer catalyst THE DOW CHEMICAL COMPANY (US) 1995-02-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220009943-A1 Tetracarboxylic Acid Dianhydride and Method for Preparing the Same TET1, HDHD5, TET3 TDP1 1415/4885THRB 4139/4885MEN1 2578/4885
US-11530228-B2 Tetracarboxylic acid dianhydride and method for preparing the same TET1, HDHD5, TET3 TDP1 1415/4885THRB 4139/4885MEN1 2578/4885
US-20220010071-A1 Polyimide Precursor, Polyimide Precursor Composition, Polyimide Film, Method for Preparing the Same, and Use Thereof PARG, PARN, PUF60 TDP1 2475/4885THRB 4676/4885MEN1 1287/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.