Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 4/20 | 0.35 |
| ▸ | TDO2 | P48775 | 4/20 | 0.35 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9630707 | 0.80 | ADRA2C (0.40) | ADRA2CADRA2AADRA2BGABRA1GABRB2 | |
| SCHEMBL10348036 | 0.77 | ADRA2C (0.45) | ADRA2CADRA2AADRA2BGABRA1GABRB2 | |
| SCHEMBL8118870 | 0.77 | XDH (0.45) | ADRA2CADRA2AADRA2BGABRA1GABRB2 | |
| SCHEMBL11872427 | 0.77 | SMN1; SMN2 (0.44) | ADRA2CADRA2AADRA2BGABRA1GABRB2 | |
| SCHEMBL24353892 | 0.77 | GABRA1 (0.42) | ADRA2CADRA2AADRA2BGABRA1GABRB2 | |
| SCHEMBL23748247 | 0.77 | ADRA2C (0.39) | ADRA2CADRA2AADRA2BGABRA1GABRB2 | |
| SCHEMBL601036 | 0.75 | GABRA1 (0.45) | ADRA2CADRA2AADRA2BGABRA1GABRB2 | |
| SCHEMBL23501592 | 0.75 | ADRA2C (0.43) | ADRA2CADRA2AADRA2BGABRA1GABRB2 | |
| SCHEMBL11874663 | 0.72 | ADRA2C (0.49) | ADRA2CADRA2AADRA2BGABRA1GABRB2 | |
| SCHEMBL1501851 | 0.72 | ADRA2C (0.49) | ADRA2CADRA2AADRA2BGABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106866377-B | Ether bond breaking method of phenyl alkyl ether | 荆楚理工学院 | 2020-06-09 | — | — | CN | disclosed |
| US-5541286-A | Bradykinin antagonist pseudopeptide derivatives of olefinic aminoalkanoic acids | SCIOS NOVA INC. (US) | 1996-07-30 | — | — | US | disclosed |
| US-5444048-A | Antiinflammatory agents, analgesics | SCIOS NOVA, INC. (US) | 1995-08-22 | — | — | US | disclosed |