Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | EP300 | Q09472 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985336 | 0.85 | MAPK14 (0.45) | MAPK14OPRD1PTGS2L3MBTL1NPC1 | |
| SCHEMBL8985532 | 0.85 | MAPK14 (0.53) | MAPK14OPRD1PTGS2L3MBTL1NPC1 | |
| SCHEMBL8985365 | 0.81 | PTGS1 (0.35) | OPRD1PTGS2L3MBTL1NPC1TDP1 | |
| SCHEMBL8985514 | 0.81 | PTGS2 (0.42) | OPRD1PTGS2L3MBTL1NPC1TDP1 | |
| SCHEMBL8985419 | 0.81 | MAPK14 (0.52) | MAPK14OPRD1PTGS2L3MBTL1NPC1 | |
| SCHEMBL8985272 | 0.81 | MAPK14 (0.52) | MAPK14OPRD1PTGS2L3MBTL1NPC1 | |
| SCHEMBL8985338 | 0.80 | MAPK14 (0.46) | MAPK14OPRD1PTGS2L3MBTL1NPC1 | |
| SCHEMBL8985533 | 0.79 | OPRD1 (0.64) | MAPK14OPRD1PTGS2L3MBTL1NPC1 | |
| SCHEMBL8985312 | 0.77 | MAPK14 (0.48) | MAPK14OPRD1PTGS2NPC1PTGS1 | |
| SCHEMBL8985370 | 0.77 | MAPK14 (0.53) | MAPK14OPRD1PTGS2L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| EP-0593761-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |
| WO-1991019708-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-26 | — | — | WO | disclosed |