Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | UBE2N | P61088 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.30 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.30 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985449 | 0.90 | OPRD1 (0.38) | MAPK14OPRD1NOX1L3MBTL1PTGS1 | |
| SCHEMBL8985530 | 0.85 | MAPK14 (0.52) | MAPK14OPRD1L3MBTL1PTGS1PTGS2 | |
| SCHEMBL8985463 | 0.82 | PTGS1 (0.35) | NOX1L3MBTL1PTGS1PTGS2UBE2N | |
| SCHEMBL8985493 | 0.82 | PTGS1 (0.41) | NOX1L3MBTL1PTGS1PTGS2UBE2N | |
| SCHEMBL8985255 | 0.82 | MAPK14 (0.45) | MAPK14OPRD1PTGS1PTGS2 | |
| SCHEMBL8985419 | 0.80 | MAPK14 (0.52) | MAPK14OPRD1L3MBTL1PTGS1PTGS2 | |
| SCHEMBL8985272 | 0.80 | MAPK14 (0.52) | MAPK14OPRD1L3MBTL1PTGS1PTGS2 | |
| SCHEMBL8985226 | 0.80 | MAPK14 (0.47) | MAPK14OPRD1L3MBTL1PTGS1PTGS2 | |
| SCHEMBL8985322 | 0.79 | PTGS2 (0.33) | PTGS1PTGS2 | |
| SCHEMBL8985533 | 0.78 | OPRD1 (0.64) | MAPK14OPRD1L3MBTL1PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| EP-0593761-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |
| WO-1991019708-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-26 | — | — | WO | disclosed |