Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18756738 | 0.96 | HTT (0.50) | TGM2MAOBHTTLMNASMN1; SMN2 | |
| SCHEMBL12094113 | 0.94 | LGALS3 (0.54) | TGM2MAOBHTTLGALS8 | |
| SCHEMBL19036050 | 0.94 | LGALS3 (0.54) | TGM2MAOBHTTLGALS8 | |
| SCHEMBL12094119 | 0.94 | LGALS3 (0.54) | TGM2MAOBHTTLGALS8 | |
| SCHEMBL28333071 | 0.92 | LMNA (0.54) | MAOBHTTLMNASMN1; SMN2LGALS8 | |
| SCHEMBL30391620 | 0.91 | HTT (0.46) | TGM2MAOBHTTLMNASMN1; SMN2 | |
| SCHEMBL30891388 | 0.91 | TGM2 (0.44) | TGM2MAOBHTTLMNASMN1; SMN2 | |
| SCHEMBL30891325 | 0.91 | HTT (0.46) | TGM2MAOBHTTLMNASMN1; SMN2 | |
| SCHEMBL30891438 | 0.89 | HTT (0.43) | TGM2MAOBHTTLMNASMN1; SMN2 | |
| SCHEMBL30391867 | 0.89 | LMNA (0.43) | TGM2MAOBHTTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491083-A | SEPARATION OF BIOMASS, DIAGNOTIC ASSAY, BIOSENSORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-02-13 | — | — | US | disclosed |
| US-5384254-A | For preparation of biosensors for medical diagnosis by immobilization og enzymes or ionic or nonionic groups | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-01-24 | — | — | US | disclosed |
| US-5342772-A | Activating with a poly(fluoroalkyl)sugar reagent | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-08-30 | — | — | US | disclosed |
| US-5243037-A | Compounds for medical diagnosis and biosensors | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-09-07 | — | — | US | disclosed |
| WO-1992005444-A1 | POLY(FLUOROALKYL) SUGAR REAGENTS AND THEIR USE FOR SURFACE MODIFICATION | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-04-02 | — | — | WO | disclosed |