Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.75 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | GRM6 | O15303 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5250495 | 0.86 | MAPK14 (1.00) | MAPK14PTGS2PTGS1GRM6HPGD | |
| SCHEMBL8985362 | 0.84 | OPRD1 (0.71) | MAPK14OPRD1PTGS2PTGS1KDM4E | |
| SCHEMBL8985383 | 0.84 | MAPK14 (0.70) | MAPK14OPRD1PTGS2PTGS1KDM4E | |
| SCHEMBL8985484 | 0.81 | OPRD1 (0.62) | MAPK14OPRD1PTGS2PTGS1MAPT | |
| SCHEMBL8985276 | 0.81 | OPRD1 (0.66) | MAPK14OPRD1PTGS2PTGS1KDM4E | |
| SCHEMBL6018669 | 0.79 | MAPK14 (0.65) | MAPK14OPRD1GRM6KDM4EMAPT | |
| SCHEMBL3602085 | 0.79 | MAPK14 (0.65) | MAPK14PTGS2PTGS1GRM6KDM4E | |
| SCHEMBL3605760 | 0.77 | MAPK14 (0.66) | MAPK14OPRD1PTGS2PTGS1GRM6 | |
| SCHEMBL27683124 | 0.77 | MAPK14 (0.62) | MAPK14PTGS2PTGS1GRM6KDM4E | |
| SCHEMBL3598457 | 0.77 | MAPK14 (0.65) | MAPK14PTGS2PTGS1GRM6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| EP-0593761-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |
| WO-1991019708-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-26 | — | — | WO | disclosed |