Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.62 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | EP300 | Q09472 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CLK1 | P49759 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985468 | 0.94 | OPRD1 (0.70) | OPRD1MAPK14PTGS2PTGS1EP300 | |
| SCHEMBL8985467 | 0.91 | MAPK14 (0.60) | OPRD1MAPK14PTGS2PTGS1NPC1 | |
| SCHEMBL8985225 | 0.86 | MAPK14 (0.55) | OPRD1MAPK14PTGS2PTGS1NPC1 | |
| SCHEMBL8985383 | 0.86 | MAPK14 (0.70) | OPRD1MAPK14PTGS2PTGS1EP300 | |
| SCHEMBL8985362 | 0.86 | OPRD1 (0.71) | OPRD1MAPK14PTGS2PTGS1EP300 | |
| SCHEMBL8985230 | 0.85 | OPRD1 (0.60) | OPRD1PTGS2PTGS1EP300NPC1 | |
| SCHEMBL8985446 | 0.84 | OPRD1 (0.58) | OPRD1PTGS2PTGS1EP300HPGD | |
| SCHEMBL8985495 | 0.82 | MAPK14 (0.52) | OPRD1MAPK14PTGS2PTGS1NPC1 | |
| SCHEMBL8985323 | 0.82 | MAPK14 (0.52) | OPRD1MAPK14PTGS2PTGS1NPC1 | |
| SCHEMBL8985276 | 0.82 | OPRD1 (0.66) | OPRD1MAPK14PTGS2PTGS1EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| EP-0593761-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |
| WO-1991019708-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-26 | — | — | WO | disclosed |