Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.43 |
| ▸ | EP300 | Q09472 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985341 | 0.93 | EP300 (0.41) | SLC6A4SLC6A2SLC6A3EP300PTGS1 | |
| SCHEMBL8985538 | 0.87 | PTGS1 (0.51) | SLC6A4SLC6A2SLC6A3EP300PTGS1 | |
| Hydrochloric Acid SCHEMBL8985440 | 0.86 | PTGS1 (0.50) | SLC6A4SLC6A2SLC6A3EP300PTGS1 | |
| SCHEMBL8985455 | 0.85 | SLC6A4 (0.48) | SLC6A4SLC6A2SLC6A3EP300ALDH1A1 | |
| SCHEMBL8985394 | 0.85 | PTGS1 (0.37) | SLC6A4SLC6A2SLC6A3EP300ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8985264 | 0.79 | PTGS2 (0.52) | PTGS1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8985480 | 0.78 | SLC6A4 (0.43) | SLC6A4SLC6A2SLC6A3EP300PTGS1 | |
| SCHEMBL8985346 | 0.76 | PTGS1 (0.48) | SLC6A4SLC6A2SLC6A3EP300LMNA | |
| SCHEMBL8985223 | 0.76 | PTGS2 (0.50) | EP300PTGS1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8985209 | 0.74 | SMN1; SMN2 (0.45) | ALDH1A1LMNAGAASMN1; SMN2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |