Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 2/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.34 |
| ▸ | MTOR | P42345 | 6/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.33 |
| ▸ | ABL1 | P00519 | 4/20 | 0.33 |
| ▸ | SRC | P12931 | 4/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.33 |
| ▸ | EGFR | P00533 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7321184 | 0.80 | PIK3CD (0.40) | CFTRPIK3CAMTORPIK3CDABL1 | |
| SCHEMBL7312127 | 0.77 | PDE5A (0.42) | PDE5APIK3CAMTORPIK3CDABL1 | |
| SCHEMBL7307551 | 0.74 | SRC (0.34) | PDE5ACFTRCSNK1A1CSNK1DCSNK1E | |
| SCHEMBL7307567 | 0.74 | SIGMAR1 (0.43) | PDE5AHDAC1PIK3CAMTORPIK3CD | |
| SCHEMBL7320063 | 0.73 | EGFR (0.39) | PDE5AKDM4EALDH1A1HSD17B10PIK3CA | |
| SCHEMBL7313010 | 0.72 | EGFR (0.36) | PDE5AKDM4EALDH1A1HSD17B10PIK3CA | |
| SCHEMBL7317680 | 0.71 | SRC (0.38) | PDE5AKDM4EALDH1A1HSD17B10PIK3CA | |
| SCHEMBL7312223 | 0.67 | TLR9 (0.39) | PDE5AKDM4EALDH1A1MAPK1HSD17B10 | |
| SCHEMBL7322196 | 0.66 | SRC (0.40) | PDE5APIK3CAMTORPIK3CDABL1 | |
| SCHEMBL9081191 | 0.63 | PDE4A (0.36) | PIK3CAMTORPIK3CDABL1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541187-A | HYPOTENSIVE AGENTS | STERLING WINTHROP INC. (US) | 1996-07-30 | — | — | US | disclosed |