Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 5/20 | 0.43 |
| ▸ | MMP9 | P14780 | 5/20 | 0.43 |
| ▸ | MMP8 | P22894 | 5/20 | 0.43 |
| ▸ | MMP13 | P45452 | 5/20 | 0.43 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987618 | 0.86 | MMP2 (0.59) | MAPTRECQLBLMCACNA1BAPBA1 | |
| SCHEMBL8987520 | 0.84 | MMP13 (0.54) | MAPTRECQLBLMCACNA1BAPBA1 | |
| SCHEMBL7469008 | 0.79 | MAPT (0.50) | MAPTRECQLBLMCACNA1BAPBA1 | |
| SCHEMBL7467562 | 0.79 | MAPT (0.44) | MAPTRECQLBLMCACNA1BAPBA1 | |
| Hydrochloric Acid SCHEMBL7474392 | 0.78 | HRAS (0.41) | MAPTMMP2MMP9MMP8MMP13 | |
| SCHEMBL7464927 | 0.77 | CHEK2 (0.49) | MAPTMMP2MMP9MMP8MMP13 | |
| SCHEMBL8772113 | 0.76 | HPSE (0.58) | MAPTMMP2MMP9MMP8MMP13 | |
| SCHEMBL7468134 | 0.76 | MAPT (0.49) | MAPTRECQLBLMCACNA1BAPBA1 | |
| SCHEMBL8987569 | 0.76 | MAPT (0.53) | MAPTRECQLTDP1MMP2MMP9 | |
| SCHEMBL7464891 | 0.75 | MAPT (0.40) | MAPTRECQLBLMCACNA1BAPBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |