Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 6/20 | 0.49 |
| ▸ | MMP9 | P14780 | 6/20 | 0.49 |
| ▸ | MMP8 | P22894 | 6/20 | 0.49 |
| ▸ | MMP13 | P45452 | 5/20 | 0.49 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 5/20 | 0.48 |
| ▸ | GUSB | P08236 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987680 | 0.90 | MAPT (0.51) | MMP2MMP9MMP8MMP13NPBWR1 | |
| SCHEMBL7464891 | 0.85 | MAPT (0.40) | MMP2MMP9MMP8MMP13NPBWR1 | |
| SCHEMBL7473157 | 0.83 | MAPT (0.43) | MMP2MMP9MMP8MMP13NPBWR1 | |
| Hydrochloric Acid SCHEMBL8987620 | 0.83 | CHEK2 (0.50) | MMP2MMP9MMP8MMP13NPBWR1 | |
| SCHEMBL8987601 | 0.83 | MMP2 (0.50) | MMP2MMP9MMP8MMP13NPBWR1 | |
| SCHEMBL7470449 | 0.82 | MAPT (0.39) | MAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL7463872 | 0.81 | MAPT (0.39) | NPBWR1MAPTL3MBTL1 | |
| SCHEMBL7467214 | 0.80 | MAPT (0.38) | MMP2MMP9MMP8MMP13NPBWR1 | |
| SCHEMBL5217712 | 0.79 | CHEK2 (0.71) | MMP2MMP9MMP8MMP13NPBWR1 | |
| SCHEMBL5217409 | 0.77 | PRSS12 (0.54) | MMP2MMP9MMP8MMP13NPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719765-A2 | Phenylbenzimidazole derivatives | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-07-03 | — | — | EP | disclosed |