Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 3/20 | 0.36 |
| ▸ | MMP9 | P14780 | 3/20 | 0.36 |
| ▸ | MMP8 | P22894 | 3/20 | 0.36 |
| ▸ | FLT3 | P36888 | 2/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987545 | 0.85 | MMP2 (0.49) | MAPTL3MBTL1MMP2MMP9MMP8 | |
| SCHEMBL7470449 | 0.84 | MAPT (0.39) | MAPTPKMMAPK1L3MBTL1THRB | |
| Hydrochloric Acid SCHEMBL7473954 | 0.84 | MAPT (0.39) | MAPTPKMMAPK1L3MBTL1THRB | |
| SCHEMBL8987680 | 0.83 | MAPT (0.51) | MAPTL3MBTL1THRBMMP2MMP9 | |
| SCHEMBL7464927 | 0.80 | CHEK2 (0.49) | MAPTMMP2MMP9MMP8NPBWR1 | |
| SCHEMBL7463872 | 0.78 | MAPT (0.39) | MAPTPKMMAPK1L3MBTL1THRB | |
| SCHEMBL7473157 | 0.77 | MAPT (0.43) | MAPTPKMMAPK1L3MBTL1THRB | |
| SCHEMBL7467214 | 0.77 | MAPT (0.38) | MAPTPKMMAPK1L3MBTL1THRB | |
| SCHEMBL7468975 | 0.75 | MAPT (0.44) | MAPTTHRBRECQLBLMTDP1 | |
| SCHEMBL8601919 | 0.72 | CHEK2 (0.60) | MAPTTDP1MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |