Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 3/20 | 0.48 |
| ▸ | MMP2 | P08253 | 3/20 | 0.48 |
| ▸ | MMP9 | P14780 | 3/20 | 0.48 |
| ▸ | MMP8 | P22894 | 3/20 | 0.48 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GUSB | P08236 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987545 | 0.90 | MMP2 (0.49) | MAPTRAB9AL3MBTL1HTTMMP13 | |
| Hydrochloric Acid SCHEMBL8987691 | 0.84 | MAPT (0.49) | MAPTSMN1; SMN2RAB9AL3MBTL1MEN1 | |
| SCHEMBL7464891 | 0.83 | MAPT (0.40) | MAPTSMN1; SMN2L3MBTL1MEN1HTT | |
| SCHEMBL7473157 | 0.81 | MAPT (0.43) | MAPTSMN1; SMN2RAB9AL3MBTL1MEN1 | |
| SCHEMBL8611572 | 0.80 | RAB9A (0.64) | MAPTSMN1; SMN2RAB9AL3MBTL1MEN1 | |
| SCHEMBL7470449 | 0.80 | MAPT (0.39) | MAPTSMN1; SMN2RAB9AL3MBTL1KMT2A | |
| SCHEMBL7463872 | 0.79 | MAPT (0.39) | MAPTSMN1; SMN2L3MBTL1MEN1KMT2A | |
| SCHEMBL3918866 | 0.79 | MAPT (0.62) | MAPTSMN1; SMN2RAB9AL3MBTL1MEN1 | |
| SCHEMBL7467214 | 0.78 | MAPT (0.38) | MAPTSMN1; SMN2RAB9AL3MBTL1MEN1 | |
| SCHEMBL28761269 | 0.76 | RAB9A (0.80) | MAPTSMN1; SMN2RAB9AL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719765-A2 | Phenylbenzimidazole derivatives | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-07-03 | — | — | EP | disclosed |