Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987842 | 0.87 | SMN1; SMN2 (0.56) | ALDH1A1RIOK2LMNARAB9ASMN1; SMN2 | |
| SCHEMBL10082521 | 0.82 | NPC1 (0.53) | ALDH1A1LMNARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL8987776 | 0.81 | CACNA1H (0.48) | RIOK2MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL8987914 | 0.81 | CACNA1H (0.48) | RIOK2KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL8987764 | 0.79 | RIOK2 (0.51) | ALDH1A1RIOK2MEN1KMT2ACDK5 | |
| SCHEMBL8987884 | 0.78 | RIOK2 (0.72) | RIOK2MEN1KMT2ACCNE1CDK2 | |
| SCHEMBL8987866 | 0.78 | ALDH1A1 (0.46) | ALDH1A1RIOK2MEN1KMT2ARAB9A | |
| SCHEMBL8987834 | 0.78 | KMT2A (0.51) | ALDH1A1RIOK2MEN1KMT2ARAB9A | |
| SCHEMBL8987643 | 0.77 | MAPK10 (0.46) | ALDH1A1RIOK2MEN1KMT2ALMNA | |
| SCHEMBL8987760 | 0.77 | LTA4H (0.44) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556859-A | N-(4-pyrimidinyl)amide pesticides | DOWELANCO (US) | 1996-09-17 | — | — | US | disclosed |