Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | RIOK2 | Q9BVS4 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | TEK | Q02763 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.40 |
| ▸ | FLT3 | P36888 | 3/20 | 0.40 |
| ▸ | FLT4 | P35916 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | CSF1R | P07333 | 2/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8988013 | 0.86 | RIOK2 (0.48) | SMN1; SMN2RIOK2KDRTEKCSNK1D | |
| SCHEMBL8987866 | 0.81 | ALDH1A1 (0.46) | SMN1; SMN2RIOK2KDRALDH1A1MAPK10 | |
| SCHEMBL8987643 | 0.80 | MAPK10 (0.46) | LMNASMN1; SMN2RIOK2CSNK1DALDH1A1 | |
| SCHEMBL8987764 | 0.77 | RIOK2 (0.51) | SMN1; SMN2RIOK2KDRALDH1A1MAPK10 | |
| SCHEMBL8987881 | 0.77 | SMN1; SMN2 (0.45) | LMNASMN1; SMN2RIOK2CSNK1DALDH1A1 | |
| SCHEMBL8987685 | 0.77 | EPHX2 (0.47) | SMN1; SMN2RIOK2KDRTEKCSNK1D | |
| SCHEMBL8987834 | 0.77 | KMT2A (0.51) | SMN1; SMN2RIOK2CSNK1DALDH1A1MAPK10 | |
| SCHEMBL8987904 | 0.76 | CSNK1D (0.47) | LMNASMN1; SMN2RIOK2KDRTEK | |
| SCHEMBL8987813 | 0.76 | ALDH1A1 (0.49) | LMNASMN1; SMN2RIOK2ALDH1A1MAPK10 | |
| SCHEMBL8987880 | 0.76 | SCN9A (0.43) | LMNASMN1; SMN2SCN9AALDH1A1CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556859-A | N-(4-pyrimidinyl)amide pesticides | DOWELANCO (US) | 1996-09-17 | — | — | US | disclosed |