SCHEMBL8988237

SCHEMBL8988237

NC(=O)c1ccc2c(c1)nnn2-c1ccc(NNC=O)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
HPGD P15428 2/20 0.41
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA9 Q16790 2/20 0.40
DHODH Q02127 1/20 0.39
KDM4E B2RXH2 3/20 0.39
NPC1 O15118 3/20 0.39
FGFR1 P11362 1/20 0.38
RAB9A P51151 4/20 0.37
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
KCNMA1 Q12791 3/20 0.36
HCAR3 P49019 1/20 0.36
MAPT P10636 2/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPK1 P28482 1/20 0.35
RXFP1 Q9HBX9 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1249136 0.76 FGFR1 (0.46) NAMPTL3MBTL1HPGDDHODHKDM4E
SCHEMBL4795623 0.73 ALDH1A1 (0.44) L3MBTL1CA1CA2KDM4ENPC1
SCHEMBL3936368 0.73 CA12 (0.54) L3MBTL1HPGDCA12CA1CA2
SCHEMBL1250337 0.68 HCAR3 (0.48) NAMPTHPGDKCNMA1HCAR3
SCHEMBL5437652 0.68 HCAR3 (0.57) L3MBTL1HPGDKDM4ENPC1HCAR3
SCHEMBL24929605 0.68 HPGD (0.53) HPGDNPC1KMT2AMEN1ALDH1A1
SCHEMBL2490016 0.67 HCAR3 (0.60) L3MBTL1HPGDKDM4ENPC1FGFR1
SCHEMBL27704159 0.67 KDM4E (0.60) L3MBTL1HPGDDHODHKDM4ENPC1
SCHEMBL11018367 0.67 NAMPT (0.53) NAMPTHPGDKDM4EFGFR1KMT2A
SCHEMBL21409085 0.67 HCAR3 (0.73) NAMPTHPGDKDM4ENPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0393477-B1 Direct positive photosensitive material FUJI PHOTO FILM CO LTD (JP) 1996-07-03 EP disclosed
US-5104784-A Containing organic thiosulfurous and inorganic sulfurous acid derivatives; storage stable sensitivity FUJI PHOTO FILM CO., LTD. (JP) 1992-04-14 US disclosed
EP-0393477-A2 Direct positive photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 1990-10-24 EP disclosed