SCHEMBL8988259

SCHEMBL8988259

CCC(C)C(=O)N1CCCCC1

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 5/20 0.58
MMP1 P03956 1/20 0.44
MMP2 P08253 1/20 0.44
MMP8 P22894 1/20 0.44
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ALDH1A1 P00352 2/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C19 P33261 1/20 0.41
HTT P42858 1/20 0.41
DPP7 Q9UHL4 1/20 0.41
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16435173 1.00 EPHX2 (0.58) EPHX2MMP1MMP2MMP8MEN1
SCHEMBL16435186 1.00 EPHX2 (0.58) EPHX2MMP1MMP2MMP8MEN1
SCHEMBL10017777 0.98 EPHX2 (0.56) EPHX2MMP1MMP2MMP8L3MBTL1
SCHEMBL16435184 0.98 EPHX2 (0.56) EPHX2MMP1MMP2MMP8L3MBTL1
SCHEMBL18909852 0.98 EPHX2 (0.56) EPHX2MMP1MMP2MMP8L3MBTL1
SCHEMBL13257060 0.93 EPHX2 (0.56) EPHX2CYP3A4CYP2C19GAA
Hydrochloric Acid SCHEMBL5205866 0.91 EPHX2 (0.54) EPHX2CYP3A4CYP2C19GAA
SCHEMBL23241332 0.83 L3MBTL1 (0.44) EPHX2MMP1MMP2MMP8MEN1
SCHEMBL8498746 0.83 L3MBTL1 (0.44) EPHX2MMP1MMP2MMP8MEN1
SCHEMBL19565377 0.83 EPHX2 (0.44) EPHX2MMP1MMP2MMP8MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026087386-A1 ROSIN DIESTER COMPOUNDS AND USES THEREOF FIRMENICH SA (CH) 2026-04-30 WO disclosed
EP-4661972-A1 TASTE-MODIFYING COMPOSITIONS AND USES THEREOF Firmenich SA (CH) 2025-12-17 EP disclosed
WO-2024200399-A1 TASTE-MODIFYING COMPOSITIONS AND USES THEREOF FIRMENICH SA (CH) 2024-10-03 WO disclosed
US-20230278998-A1 Compound containing structure of a five-membered heteroaromatic ring, pharmaceutical compositions thereof and applications thereof 280 BIO, INC. (US) 2023-09-07 US disclosed
US-20230018460-A1 1-AMINOSULFONYL-2-CARBOXYPYRROLE DERIVATIVES AS METALLO-BETA-LACTAMASE INHIBITORS Infex Therapeutics Limited (GB) 2023-01-19 US disclosed
EP-4112308-A1 INK COMPOSITION, INK SET, AND IMAGE RECORDING METHOD FUJIFILM Corporation (JP) 2023-01-04 EP disclosed
WO-2022258043-A1 GEMCITABINE ANTICANCER DERIVATIVE AND ANTICANCER PHARMACEUTICAL USE 深圳艾欣达伟医药科技有限公司 2022-12-15 WO disclosed
EP-2496230-B1 IRE-1 ALPHA INHIBITORS FOSUN ORINOVE PHARMATECH INC (CN) 2020-02-26 EP disclosed
WO-2020022787-A1 NOVEL IMIDAZOLE DERIVATIVE HAVING JNK INHIBITORY ACTIVITY, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 삼진제약주식회사 2020-01-30 WO disclosed
US-10189986-B2 Acrylamide-based copolymers, terpolymers, and use as hydrate inhibitors SAUDI ARABIAN OIL COMPANY (SA) 2019-01-29 US disclosed
US-20170321050-A1 ACRYLAMIDE-BASED COPOLYMERS, TERPOLYMERS, AND USE AS HYDRATE INHIBITORS SAUDI ARABIAN OIL COMPANY (SA) 2017-11-09 US disclosed
US-20160291019-A1 System for Detecting Rare Cells THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2016-10-06 US disclosed
WO-2016006593-A1 NOVEL BENZOXAZINE DERIVATIVE AND MEDICINE COMPRISING SAME 国立研究開発法人国立長寿医療研究センター 2016-01-14 WO disclosed
US-8580905-B2 Polymers, compositions and methods of use for foams, laundry detergents, shower rinses and coagulants RHODIA INC. (US) 2013-11-12 US disclosed
US-8188204-B2 Polymers, compositions and methods for use for foams, laundry detergents, shower rinses and coagulants RHODIA INC. (US) 2012-05-29 US disclosed
US-20110294749-A1 DIAMINOPYRIMIDINECARBOXAMIDE DERIVATIVE ASTELLAS PHARMA INC. (JP) 2011-12-01 US disclosed
US-20110224189-A1 SUBSTITUTED CYCLIC HYDROXAMATES AS INHIBITORS OF MATRIX METALLOPROTEINASES INCYTE CORPORATION 2011-09-15 US disclosed
US-7871982-B2 Lincomycin derivatives and antimicrobial agents comprising the same as active ingredient MEIJI SEIKA KAISHA, LTD. (JP) 2011-01-18 US disclosed
US-20090156512-A1 potent activity against resistant pneumococci MEIJI SEIKA KAISHA, LTD. (JP) 2009-06-18 US disclosed
US-7435735-B2 Hydroxy pyridopyrrolopyrazine dione compounds useful as HIV integrase inhibitors MERCK & CO., INC. (US) 2008-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224189-A1 SUBSTITUTED CYCLIC HYDROXAMATES AS INHIBITORS OF MATRIX METALLOPROTEINASES MMP25, MMP14, MMP9 EPHX2 334/4885MMP1 8/4885MMP2 4/4885
US-20170321050-A1 ACRYLAMIDE-BASED COPOLYMERS, TERPOLYMERS, AND USE AS HYDRATE INHIBITORS F12, MTX1, ZYX EPHX2 628/4885MMP1 906/4885MMP2 1469/4885
US-10189986-B2 Acrylamide-based copolymers, terpolymers, and use as hydrate inhibitors F12, MTX1, ZYX EPHX2 628/4885MMP1 906/4885MMP2 1469/4885
US-20110294749-A1 DIAMINOPYRIMIDINECARBOXAMIDE DERIVATIVE STAT6, STAT4, STAT3 EPHX2 3868/4885MMP1 2982/4885MMP2 1551/4885
US-20090156512-A1 potent activity against resistant pneumococci H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, NAT1, NPM1 EPHX2 4761/4885MMP1 1186/4885MMP2 1096/4885
US-20230018460-A1 1-AMINOSULFONYL-2-CARBOXYPYRROLE DERIVATIVES AS METALLO-BETA-LACTAMASE INHIBITORS CPN1, CMBL, ALDH7A1 EPHX2 1889/4885MMP1 794/4885MMP2 346/4885
US-20230278998-A1 Compound containing structure of a five-membered heteroaromatic ring, pharmaceutical compositions thereof and applications thereof PARG, CYP3A5, CYP11B1 EPHX2 315/4885MMP1 4744/4885MMP2 2866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.