Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 7/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | KLK5 | Q9Y337 | 6/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | BUB1 | O43683 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470171 | 0.76 | NFKB1 (0.34) | MAPK1KDM4E | |
| SCHEMBL34473806 | 0.71 | KLK7 (0.36) | KLK7ELANEKLK5NR1H2MAPK1 | |
| SCHEMBL31750269 | 0.71 | KLK7 (0.36) | KLK7ELANEKLK5NR1H2MAPK1 | |
| SCHEMBL13409204 | 0.70 | USP2 (0.40) | KLK7NR1H2MAPK1KDM4EMAPT | |
| SCHEMBL27635233 | 0.69 | MAPK1 (0.43) | KLK7ELANEKLK5MAPK1KDM4E | |
| SCHEMBL18593027 | 0.69 | MAPK1 (0.43) | KLK7ELANEKLK5MAPK1KDM4E | |
| SCHEMBL22096754 | 0.69 | KLK7 (0.40) | KLK7ELANEKLK5MAPK1BUB1 | |
| SCHEMBL2836809 | 0.68 | KLK7 (0.34) | KLK7KLK5NR1H2KDM4EMAPT | |
| SCHEMBL22336304 | 0.66 | GPR119 (0.37) | NR1H2MAPK1BUB1KDM4EMAPT | |
| SCHEMBL13391280 | 0.65 | USP2 (0.36) | KLK7KLK5NR1H2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504076-A | Cephalosporin compounds | PFIZER INC. (US) | 1996-04-02 | — | — | US | disclosed |