SCHEMBL8988835

SCHEMBL8988835

CC(C)(C)OCC1NCCN(CC(=O)O)C1=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACE P12821 4/20 0.39
PKM P14618 2/20 0.38
GAA P10253 1/20 0.38
LMNA P02545 1/20 0.36
POLB P06746 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33
PLA2G10 O15496 2/20 0.32
PLA2G5 P39877 2/20 0.32
ITGB3 P05106 3/20 0.31
ITGA2B P08514 3/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP3A4 P08684 1/20 0.31
RECQL P46063 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ROCK2 O75116 1/20 0.31
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8988818 1.00 ACE (0.39) ACEPKMGAALMNAPOLB
Oxalic Acid SCHEMBL7298024 0.87 PLA2G10 (0.41) ACEPKMGAAPOLBPLA2G10
Oxalic Acid SCHEMBL7298013 0.87 PLA2G10 (0.41) ACEPKMGAAPOLBPLA2G10
SCHEMBL7311444 0.78 PKM (0.45) ACEPKMGAALMNAITGB3
SCHEMBL7311432 0.78 PKM (0.45) ACEPKMGAALMNAITGB3
SCHEMBL11084683 0.77 ACE (0.41) ACEPKMGAALMNAPOLB
SCHEMBL7309103 0.76 MEN1 (0.40) ACEGAAKMT2ATDP1ROCK2
SCHEMBL7309092 0.76 MEN1 (0.40) ACEGAAKMT2ATDP1ROCK2
SCHEMBL27381852 0.75 PKM (0.45) ACEPKMGAAPOLBCYP2D6
Hydrochloric Acid SCHEMBL7277753 0.74 PKM (0.44) ACEPKMGAAPOLBCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5550131-A ANTITHROMBOTIC AGENT TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-08-27 US disclosed