Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | VNN1 | O95497 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11445035 | 0.86 | L3MBTL1 (0.51) | L3MBTL1MAPTMRGPRX4SRD5A2MAPK1 | |
| SCHEMBL11541766 | 0.86 | L3MBTL1 (0.47) | L3MBTL1MAPTVNN1MRGPRX4SRD5A2 | |
| SCHEMBL8990053 | 0.84 | CTSL (0.49) | L3MBTL1MAPK1GRIN2BATMTDP1 | |
| Hydrochloric Acid SCHEMBL11541768 | 0.84 | L3MBTL1 (0.50) | L3MBTL1MAPTVNN1MRGPRX4SRD5A2 | |
| SCHEMBL14302252 | 0.81 | SRD5A2 (0.47) | L3MBTL1MAPTVNN1MRGPRX4SRD5A2 | |
| SCHEMBL7015547 | 0.81 | SRD5A2 (0.47) | L3MBTL1MAPTMRGPRX4SRD5A2MAPK1 | |
| SCHEMBL11445117 | 0.81 | HPGD (0.47) | L3MBTL1MAPTMRGPRX4HTTKMT2A | |
| SCHEMBL809735 | 0.79 | ATM (0.67) | L3MBTL1SRD5A2MAPK1CNR2ATM | |
| SCHEMBL1395822 | 0.78 | HTR3E (0.67) | KMT2AHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL3054667 | 0.78 | PARP1 (0.53) | L3MBTL1MAPTTDP1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716600-A1 | TOPICALLY ADMINISTRABLE COMPOSITIONS CONTAINING 3-BENZOYLPHENYLACETIC ACID DERIVATIVES FOR TREATMENT OF OPHTHALMIC INFLAMMATORY DISORDERS | ALCON LABORATORIES, INC. (US) | 1996-06-19 | — | — | EP | claimed |
| WO-1995033457-A1 | TOPICALLY ADMINISTRABLE COMPOSITIONS CONTAINING 3-BENZOYLPHENYLACETIC ACID DERIVATIVES FOR TREATMENT OF OPHTHALMIC INFLAMMATORY DISORDERS | ALCON LABORATORIES, INC. (US) | 1995-12-14 | — | — | WO | claimed |