Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAT2A | P31153 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990014 | 0.87 | HTT (0.42) | RAB9ANPC1CYP1A2HTTCYP2D6 | |
| SCHEMBL13543523 | 0.79 | RAB9A (0.54) | RAB9ANPC1HTTSMN1; SMN2MEN1 | |
| SCHEMBL4929407 | 0.73 | GAA (0.47) | RAB9ANPC1GAACYP1A2HTT | |
| SCHEMBL4929416 | 0.73 | ALDH1A1 (0.41) | RAB9ANPC1GAACYP1A2HTT | |
| SCHEMBL29178107 | 0.72 | GAA (0.59) | RAB9ANPC1GAAHTTSMN1; SMN2 | |
| Water SCHEMBL11318555 | 0.71 | GSR (0.45) | RAB9ANPC1MAT2AHTTMEN1 | |
| SCHEMBL10869503 | 0.70 | LMNA (0.52) | NPC1GAAHTTSMN1; SMN2MEN1 | |
| SCHEMBL7473993 | 0.69 | ADORA3 (0.41) | RAB9ANPC1GAASMN1; SMN2MEN1 | |
| SCHEMBL13071550 | 0.66 | CYP1A2 (0.59) | RAB9ANPC1GAACYP1A2HTT | |
| SCHEMBL13908572 | 0.65 | ADORA1 (0.53) | RAB9ANPC1GAASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552426-A | NERVOUS SYSTEM DISORDERS USING IMIDAZOLE DERIVITIVES | ELI LILLY AND COMPANY (US) | 1996-09-03 | — | — | US | disclosed |