Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990316 | 0.86 | ALDH1A1 (0.39) | LMNAKIF11ALDH1A1ALOX15KCNN4 | |
| SCHEMBL27284232 | 0.78 | LMNA (0.40) | LMNACHRM2CHRM1CHRM3MLNR | |
| SCHEMBL8990308 | 0.77 | CES1 (0.42) | CHRM3KIF11ALDH1A1ALOX15KCNN4 | |
| SCHEMBL7943850 | 0.76 | KDM4E (0.46) | LMNACHRM2CHRM1CHRM3OPRM1 | |
| SCHEMBL720308 | 0.75 | CNR1 (0.36) | MEN1KMT2ATSHRSIGMAR1 | |
| SCHEMBL13320030 | 0.75 | LMNA (0.45) | LMNACHRM2CHRM1CHRM3MLNR | |
| SCHEMBL2348691 | 0.74 | KIF11 (0.65) | LMNACHRM2CHRM1CHRM3MLNR | |
| SCHEMBL6421037 | 0.74 | KIF11 (0.43) | LMNACHRM2CHRM1CHRM3MLNR | |
| SCHEMBL8434800 | 0.74 | KIF11 (0.43) | LMNACHRM2CHRM1CHRM3MLNR | |
| SCHEMBL1356738 | 0.73 | ALDH1A1 (0.43) | LMNACHRM2CHRM1CHRM3MLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137592-A1 | PROCESS FOR PREPARING PURINE DERIVATIVE | AUROBINDO PHARMA LTD (IN) | 2010-06-03 | — | — | US | disclosed |
| US-5500484-A | FROM ALDEHYDE | KURARAY CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| EP-0641757-A1 | 2-Aryl-1,3-propanediol and dioxane derivatives and their preparation | KURARAY CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137592-A1 | PROCESS FOR PREPARING PURINE DERIVATIVE | TYMP, PNP, UMPS | LMNA 1185/4885CHRM2 4666/4885CHRM1 4417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.