Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990789 | 0.92 | CCR3 (0.33) | PRMT5GHSRHDAC1HDAC7 | |
| SCHEMBL8990995 | 0.91 | — | — | |
| SCHEMBL8991154 | 0.91 | TAS1R3 (0.32) | PRMT5PPARGMEN1KMT2APDCD1 | |
| SCHEMBL8990942 | 0.87 | PRMT5 (0.38) | PRMT5GHSRHDAC1HDAC7 | |
| SCHEMBL8990989 | 0.87 | CCR3 (0.33) | HDAC1HDAC7 | |
| SCHEMBL8990778 | 0.86 | SIGMAR1 (0.32) | HDAC1HDAC7 | |
| SCHEMBL8990967 | 0.82 | GHSR (0.45) | GHSRHDAC1HDAC7PPARGMEN1 | |
| SCHEMBL8990974 | 0.82 | GHSR (0.45) | GHSRHDAC1HDAC7PPARGMEN1 | |
| SCHEMBL8990954 | 0.81 | CCR3 (0.33) | PRMT5HDAC1HDAC7PPARG | |
| SCHEMBL8990980 | 0.81 | PRMT5 (0.38) | PRMT5HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| WO-1995009633-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-04-13 | — | — | WO | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |
| WO-1995009633-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-04-13 | — | — | WO | disclosed |