Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 9/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990867 | 0.95 | CCR3 (0.34) | CCR3CYP2D6TACR1FAAHCNR1 | |
| SCHEMBL8990942 | 0.93 | PRMT5 (0.38) | TACR1PRMT5HDAC1HDAC7 | |
| SCHEMBL8991043 | 0.91 | AGTR1 (0.34) | PRMT5AGTR1AGTR2PPARG | |
| SCHEMBL8990819 | 0.91 | PRMT5 (0.32) | TACR1PRMT5HDAC1HDAC7 | |
| SCHEMBL8990789 | 0.87 | CCR3 (0.33) | CCR3CYP2D6PRMT5FAAHCNR1 | |
| SCHEMBL8990980 | 0.87 | PRMT5 (0.38) | TACR1PRMT5HDAC1HDAC7 | |
| SCHEMBL8991074 | 0.86 | AGTR1 (0.35) | AGTR1AGTR2PPARG | |
| SCHEMBL8990688 | 0.86 | HDAC1 (0.31) | TACR1PRMT5AGTR1HDAC1HDAC7 | |
| SCHEMBL8990864 | 0.83 | ANPEP (0.36) | CCR3CYP2D6FAAHCNR1CNR2 | |
| SCHEMBL8991029 | 0.82 | GHSR (0.42) | CCR3CYP2D6TACR1FAAHCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| WO-1995009633-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-04-13 | — | — | WO | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |
| WO-1995009633-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-04-13 | — | — | WO | disclosed |