Sugi Predict

Sugi Predict / Compounds / SCHEMBL899079

SCHEMBL899079

SCHEMBL899079

COc1cc(Cl)c2ccccc2n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 2/20 0.50
▸ LMNA P02545 3/20 0.47
▸ L3MBTL1 Q9Y468 1/20 0.47
▸ KDM4E B2RXH2 5/20 0.46
▸ ALDH1A1 P00352 5/20 0.46
▸ HPGD P15428 3/20 0.46
▸ MEN1 O00255 2/20 0.46
▸ KMT2A Q03164 2/20 0.46
▸ MAOA P21397 1/20 0.45
▸ MAOB P27338 1/20 0.45
▸ SMN1; SMN2 Q16637 1/20 0.45
▸ NR1I3 Q14994 1/20 0.44
▸ ALOX15 P16050 1/20 0.42
▸ MAPT P10636 3/20 0.41
▸ NPC1 O15118 2/20 0.41
▸ NQO2 P16083 1/20 0.41
▸ MAPK1 P28482 2/20 0.41
▸ RAB9A P51151 1/20 0.41
▸ GLA P06280 1/20 0.41
▸ GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30344059 1.00 POLB (0.50) POLBLMNAL3MBTL1KDM4EALDH1A1
SCHEMBL5639914 0.80 POLB (0.47) POLBKDM4EALDH1A1HPGDMEN1
SCHEMBL423891 0.79 L3MBTL1 (0.71) POLBLMNAL3MBTL1KDM4EALDH1A1
SCHEMBL396614 0.79 HPGD (0.64) POLBLMNAL3MBTL1KDM4EALDH1A1
SCHEMBL30065410 0.79 HPGD (0.64) POLBLMNAL3MBTL1KDM4EALDH1A1
SCHEMBL7814367 0.79 LMNA (0.64) LMNAL3MBTL1KDM4EALDH1A1HPGD
SCHEMBL14300444 0.78 POLB (0.50) POLBLMNAL3MBTL1KDM4EALDH1A1
SCHEMBL7814765 0.78 KDM4E (0.59) KDM4EALDH1A1HPGDNQO2
SCHEMBL28611035 0.78 HPGD (0.62) POLBLMNAL3MBTL1KDM4EALDH1A1
SCHEMBL3155421 0.78 POLB (0.50) POLBLMNAL3MBTL1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12612384-B2 Heterocyclic CYP4A inhibitor compounds and compositions thereof MBD Co., Ltd. (KR) 2026-04-28 — — US disclosed
US-12479821-B2 Quinoline compound and use thereof MBD Co., Ltd. (KR) 2025-11-25 — — US disclosed
US-20250025443-A1 COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES Clear Creek Bio, Inc. (US) 2025-01-23 — — US disclosed
US-20240287032-A1 NOVEL HETEROCYCLIC COMPOUND AND USE THEREOF MBD Co., Ltd. (KR) 2024-08-29 — — US disclosed
CN-117659025-A TOLL-like receptor 8 (TLR 8) specific antagonists, methods of making and uses thereof 科罗拉多州立大学董事会法人团体 2024-03-08 — — CN disclosed
CN-117586108-A TOLL-like receptor 8 (TLR 8) specific antagonists, methods of making and uses thereof 科罗拉多州立大学董事会法人团体 2024-02-23 — — CN disclosed
CN-117586191-A TOLL-like receptor 8 (TLR 8) specific antagonists, methods of making and uses thereof 科罗拉多州立大学董事会法人团体 2024-02-23 — — CN disclosed
CN-111542515-B TOLL-like receptor 8 (TLR 8) specific antagonists, methods of making and uses thereof 科罗拉多州立大学董事会法人团体 2023-12-05 — — CN disclosed
US-20230132035-A1 Toll-Like Receptor 8 (TLR8)-Specific Antagonists and Methods of Making and Uses Thereof UNIV COLORADO REGENTS (US) 2023-04-27 — — US disclosed
WO-2023064493-A1 COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES Clear Creek Bio, Inc. (US) 2023-04-20 — — WO disclosed
EP-2621903-B1 N-HETEROARYL COMPOUNDS INTERVET INT BV (NL) 2017-03-01 — — EP disclosed
US-8877934-B2 N-heteroaryl compounds INTERVET INC. (US) 2014-11-04 — — US disclosed
EP-2621903-A1 N-HETEROARYL COMPOUNDS Intervet International B.V. (NL) 2013-08-07 — — EP disclosed
US-20130196993-A1 N-HETEROARYL COMPOUNDS INTERVET INC. 2013-08-01 — — US disclosed
WO-2012041873-A1 N-HETEROARYL COMPOUNDS INTERVET INTERNATIONAL B.V. (NL) 2012-04-05 — — WO disclosed
EP-1105413-B1 HEPATITIS C INHIBITOR TRI-PEPTIDES BOEHRINGER INGELHEIM CA LTD (CA) 2009-04-29 — — EP disclosed
WO-2002026713-A1 ANTIPARASITIC COMPOUNDS KING'S COLLEGE LONDON (GB) 2002-04-04 — — WO disclosed
EP-0317188-B1 Heteroaromatic enamide derivatives and their use as pesticides ROUSSEL UCLAF (FR) 1995-09-27 — — EP disclosed
US-5114940-A Insecticides or anthelmintics from fused ring heterocycles containing amides or thioamides ROUSSEL-UCLAF (FR) 1992-05-19 — — US disclosed
EP-0317188-A2 Heteroaromatic enamide derivatives and their use as pesticides ROUSSEL UCLAF (FR) 1989-05-24 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240287032-A1 NOVEL HETEROCYCLIC COMPOUND AND USE THEREOF CYP4B1, CYP4A11, CYP3A4 POLB 4075/4885LMNA 3776/4885L3MBTL1 4482/4885
US-12479821-B2 Quinoline compound and use thereof CYP4A11, CYP7A1, CYP4B1 POLB 4120/4885LMNA 3175/4885L3MBTL1 4514/4885
US-12612384-B2 Heterocyclic CYP4A inhibitor compounds and compositions thereof CYP4A11, CYP4B1, CYP4A22 POLB 1807/4885LMNA 1803/4885L3MBTL1 3606/4885
US-20130196993-A1 N-HETEROARYL COMPOUNDS HNMT, SQLE, PIGO POLB 4035/4885LMNA 1785/4885L3MBTL1 3255/4885
US-20230132035-A1 Toll-Like Receptor 8 (TLR8)-Specific Antagonists and Methods of Making and Uses Thereof TLR8, TLR3, TLR9 POLB 2730/4885LMNA 3870/4885L3MBTL1 3008/4885
US-20250025443-A1 COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES ACE, PREP, PEPD POLB 879/4885LMNA 627/4885L3MBTL1 3477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.