Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | FPR1 | P21462 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990940 | 0.95 | KMT2A (0.35) | KMT2ANPSR1ADRB2ADRB1ADRB3 | |
| SCHEMBL8991085 | 0.92 | ADRB2 (0.38) | KMT2ANPSR1ADRB2ADRB1ADRB3 | |
| SCHEMBL8990830 | 0.92 | ADRB2 (0.36) | ADRB2ADRB1ADRB3ALDH1A1LMNA | |
| SCHEMBL8990896 | 0.91 | ADRB2 (0.33) | ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL8990996 | 0.90 | KMT2A (0.38) | KMT2ANPSR1TP53ALDH1A1KDM4E | |
| SCHEMBL8990826 | 0.89 | FPR1 (0.34) | KMT2ANPSR1ALDH1A1KDM4ELMNA | |
| SCHEMBL8991053 | 0.88 | GHSR (0.33) | KMT2ANPSR1MAPTFPR1FPR2 | |
| SCHEMBL8990882 | 0.87 | ADRB2 (0.35) | KMT2ANPSR1ADRB2ADRB1ADRB3 | |
| SCHEMBL8990950 | 0.86 | ADRB2 (0.33) | KMT2ANPSR1ADRB2ADRB1ADRB3 | |
| SCHEMBL8990892 | 0.86 | ADRB2 (0.31) | ADRB2ADRB1ADRB3ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |