Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990892 | 0.95 | ADRB2 (0.31) | ADRB2ADRB1ADRB3TSHRROCK2 | |
| SCHEMBL8991085 | 0.92 | ADRB2 (0.38) | ADRB2ADRB1ADRB3TSHRROCK2 | |
| SCHEMBL8990830 | 0.92 | ADRB2 (0.36) | ADRB2ADRB1ADRB3TSHRROCK2 | |
| SCHEMBL8990868 | 0.91 | KMT2A (0.34) | ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL8990749 | 0.89 | GHSR (0.31) | — | |
| SCHEMBL8991081 | 0.88 | GHSR (0.33) | — | |
| SCHEMBL8990882 | 0.87 | ADRB2 (0.35) | ADRB2ADRB1ADRB3TSHRROCK2 | |
| SCHEMBL8990950 | 0.86 | ADRB2 (0.33) | ADRB2ADRB1ADRB3TSHRROCK2 | |
| SCHEMBL8990940 | 0.86 | KMT2A (0.35) | ADRB2ADRB1ADRB3 | |
| SCHEMBL8990875 | 0.84 | GHSR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |