Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990908 | 0.94 | GAA (0.35) | ADRB2ADRB1ADRB3TSHRGAA | |
| SCHEMBL8990830 | 0.88 | ADRB2 (0.36) | ADRB2ADRB1ADRB3TSHRGAA | |
| SCHEMBL8991035 | 0.88 | MME (0.36) | AGTR1GHSRTACR1MMEACE | |
| SCHEMBL7791792 | 0.84 | GHSR (0.49) | AGTR1GHSR | |
| SCHEMBL8990851 | 0.84 | TACR1 (0.38) | AGTR1GHSRTACR1MMEACE | |
| SCHEMBL8991085 | 0.83 | ADRB2 (0.38) | ADRB2ADRB1ADRB3TSHRGAA | |
| SCHEMBL8990868 | 0.82 | KMT2A (0.34) | ADRB2ADRB1ADRB3TSHRALDH1A1 | |
| SCHEMBL8990896 | 0.82 | ADRB2 (0.33) | ADRB2ADRB1ADRB3TSHRNAMPT | |
| SCHEMBL8990950 | 0.82 | ADRB2 (0.33) | ADRB2ADRB1ADRB3TSHRGAA | |
| SCHEMBL8991127 | 0.81 | MME (0.36) | AGTR1GHSRTACR1MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |
| WO-1995009633-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-04-13 | — | — | WO | disclosed |