Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | GLA | P06280 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | CASP1 | P29466 | 4/20 | 0.46 |
| ▸ | CASP7 | P55210 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991320 | 0.90 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4EGLAGAA | |
| SCHEMBL8991267 | 0.88 | KDM4E (0.48) | ALDH1A1HPGDKDM4EGLAGAA | |
| SCHEMBL8991286 | 0.88 | GAA (0.41) | ALDH1A1HPGDKDM4EGLAGAA | |
| SCHEMBL8991357 | 0.87 | MEN1 (0.48) | ALDH1A1HPGDKDM4EGLAGAA | |
| SCHEMBL8991400 | 0.86 | MEN1 (0.36) | ALDH1A1HPGDKDM4EGLAGAA | |
| SCHEMBL8991066 | 0.81 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4EGLAGAA | |
| SCHEMBL8991328 | 0.81 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4EGLAGAA | |
| SCHEMBL8991130 | 0.80 | MEN1 (0.39) | ALDH1A1HPGDKDM4EGAAHSD17B10 | |
| SCHEMBL8991316 | 0.80 | ALDH1A1 (0.55) | ALDH1A1HPGDKDM4EGLAGAA | |
| SCHEMBL8991138 | 0.79 | ABL1 (0.43) | ALDH1A1HPGDHSD17B10NPSR1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |