Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | GLA | P06280 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | CASP1 | P29466 | 4/20 | 0.44 |
| ▸ | CASP7 | P55210 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | PDE1B | Q01064 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | AURKA | O14965 | 2/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991288 | 0.89 | MEN1 (0.40) | HSD17B10KDM4EGAAMAPK1HDAC1 | |
| SCHEMBL8991284 | 0.89 | KDM4E (0.44) | ALDH1A1HPGDHSD17B10KDM4EGLA | |
| SCHEMBL8991361 | 0.89 | MEN1 (0.46) | ALDH1A1HPGDHSD17B10KDM4EGAA | |
| SCHEMBL8991137 | 0.82 | AURKA (0.40) | ALDH1A1HSD17B10KDM4EMAPK1MAPT | |
| SCHEMBL8991328 | 0.82 | ALDH1A1 (0.44) | ALDH1A1HPGDHSD17B10KDM4EGLA | |
| SCHEMBL8991320 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HPGDHSD17B10KDM4EGLA | |
| SCHEMBL8991047 | 0.81 | ALDH1A1 (0.46) | ALDH1A1HPGDHSD17B10KDM4EGLA | |
| SCHEMBL8991143 | 0.80 | HDAC1 (0.46) | ALDH1A1HPGDHSD17B10NPSR1HDAC1 | |
| SCHEMBL8991300 | 0.79 | PDE4A (0.43) | ALDH1A1HSD17B10KDM4ENPSR1MAPK1 | |
| SCHEMBL8991176 | 0.78 | XDH (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |