Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | BCR | P11274 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 2/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991063 | 0.88 | GAA (0.41) | HDAC1HDAC6LMNAALDH1A1MAPT | |
| SCHEMBL8991388 | 0.87 | PDE4A (0.50) | LMNAALDH1A1MAPTSMN1; SMN2HPGD | |
| SCHEMBL8991141 | 0.86 | PDE4A (0.38) | ABL1BCRHDAC1HDAC6TP53 | |
| SCHEMBL8991089 | 0.86 | EGFR (0.45) | ABL1HPGD | |
| SCHEMBL8991143 | 0.81 | HDAC1 (0.46) | ABL1BCRHDAC1HDAC6LMNA | |
| SCHEMBL8991047 | 0.79 | ALDH1A1 (0.46) | ABL1BCRHDAC1HDAC6LMNA | |
| SCHEMBL8991225 | 0.77 | PDE4A (0.42) | ABL1ALDH1A1SMN1; SMN2HPGDPDE4A | |
| SCHEMBL8991231 | 0.77 | GAA (0.41) | HDAC1HDAC6LMNAALDH1A1MAPT | |
| SCHEMBL8991249 | 0.76 | ADK (0.33) | — | |
| SCHEMBL8991103 | 0.76 | PDE4A (0.50) | LMNAALDH1A1MAPTSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |