Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 7/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991147 | 0.89 | GAA (0.39) | MEN1KMT2ANPC1RAB9APDE4A | |
| SCHEMBL8991185 | 0.89 | KDM4E (0.41) | CCR9RETMEN1KMT2ADOT1L | |
| SCHEMBL8990972 | 0.88 | MEN1 (0.46) | MEN1KMT2ANPC1RAB9APDE4A | |
| SCHEMBL8991328 | 0.86 | ALDH1A1 (0.44) | MEN1KMT2ANPC1RAB9ATP53 | |
| SCHEMBL8991094 | 0.82 | MEN1 (0.37) | CCR9RETMEN1KMT2ANPC1 | |
| SCHEMBL8991238 | 0.82 | AURKA (0.40) | MEN1KMT2ANPC1RAB9APDE4A | |
| SCHEMBL8991400 | 0.81 | MEN1 (0.36) | CCR9RETMEN1KMT2ANPC1 | |
| SCHEMBL8991272 | 0.80 | PDE4A (0.38) | RETKMT2APDE4APDE4BPDE4C | |
| SCHEMBL8991129 | 0.79 | PDE4A (0.41) | MEN1KMT2ANPC1RAB9APDE4A | |
| SCHEMBL8991067 | 0.77 | KDM4E (0.39) | CCR9MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |